"Cell Adhesion Molecule-1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cell adhesion molecule that contains extracellular immunoglobulin V and C2 domains. It mediates homophilic and heterophilic cell-cell adhesion independently of calcium, and acts as a tumor suppressor in NON-SMALL-CELL LUNG CANCER (NSCLC) cells. Its interaction with NATURAL KILLER CELLS is important for their cytotoxicity and its expression by MAST CELLS plays a role in their interaction with neurons; it may also function in synapse assembly, nerve growth and differentiation.
| Descriptor ID |
D000075982
|
| MeSH Number(s) |
D12.776.395.550.200.115 D12.776.543.550.200.128 D23.050.301.350.115
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| Concept/Terms |
Cell Adhesion Molecule-1- Cell Adhesion Molecule-1
- Adhesion Molecule-1, Cell
- Cell Adhesion Molecule 1
- Molecule-1, Cell Adhesion
- CADM1 Protein
- Tumor Suppressor in Lung Cancer 1 Protein
- IGSF4 Protein
- TSLC1 Protein
|
Below are MeSH descriptors whose meaning is more general than "Cell Adhesion Molecule-1".
Below are MeSH descriptors whose meaning is more specific than "Cell Adhesion Molecule-1".
This graph shows the total number of publications written about "Cell Adhesion Molecule-1" by people in this website by year, and whether "Cell Adhesion Molecule-1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2019 | 1 | 0 | 1 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Cell Adhesion Molecule-1" by people in Profiles.
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Baqai U, Purwin TJ, Bechtel N, Chua V, Han A, Hartsough EJ, Kuznetsoff JN, Harbour JW, Aplin AE. Multi-omics Profiling Shows BAP1 Loss Is Associated with Upregulated Cell Adhesion Molecules in Uveal Melanoma. Mol Cancer Res. 2022 08 05; 20(8):1260-1271.
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Hartsough EJ, Weiss MB, Heilman SA, Purwin TJ, Kugel CH, Rosenbaum SR, Erkes DA, Tiago M, HooKim K, Chervoneva I, Aplin AE. CADM1 is a TWIST1-regulated suppressor of invasion and survival. Cell Death Dis. 2019 03 25; 10(4):281.