"CD52 Antigen" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A small GPI-linked glycoprotein expressed on the surface of normal and malignant B-CELLS; T-CELLS; MONOCYTES; MACROPHAGES; NK CELLS; and GRANULOCYTES. It is expressed densely and without modulation in many malignant T-cell neoplasms and therefore a target for antibody therapies (e.g., ALEMTUZUMAB).
| Descriptor ID |
D000074301
|
| MeSH Number(s) |
D12.776.395.550.448.190 D12.776.543.484.500.190 D12.776.543.550.418.190 D23.050.285.022 D23.101.100.943
|
| Concept/Terms |
CD52 Antigen- CD52 Antigen
- CDw52 Antigen
- Campath-1 Antigen
- Campath 1 Antigen
- Campath-1H Antigen
- Campath 1H Antigen
- Lymphocyte Antigen CDw52
- CDw52, Lymphocyte Antigen
- Lymphocyte Antigen CD52
- CD52, Lymphocyte Antigen
- Campath-1 Receptor
- Campath 1 Receptor
- HLA-Bw52 Antigen
- HLA Bw52 Antigen
- HLA-Bw52
- HLA Bw52
- Cambridge Pathology 1 Antigen
- CD52 Protein
|
Below are MeSH descriptors whose meaning is more general than "CD52 Antigen".
Below are MeSH descriptors whose meaning is more specific than "CD52 Antigen".
This graph shows the total number of publications written about "CD52 Antigen" by people in this website by year, and whether "CD52 Antigen" was a major or minor topic of these publications.
To see the data from this visualization as text,
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
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Below are the most recent publications written about "CD52 Antigen" by people in Profiles.
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Zhang X, Tao Y, Chopra M, Ahn M, Marcus KL, Choudhary N, Zhu H, Markovic-Plese S. Differential reconstitution of T cell subsets following immunodepleting treatment with alemtuzumab (anti-CD52 monoclonal antibody) in patients with relapsing-remitting multiple sclerosis. J Immunol. 2013 Dec 15; 191(12):5867-74.
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Magro CM, Morrison CD, Heerema N, Porcu P, Sroa N, Deng AC. T-cell prolymphocytic leukemia: an aggressive T cell malignancy with frequent cutaneous tropism. J Am Acad Dermatol. 2006 Sep; 55(3):467-77.
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Zhang Z, Zhang M, Goldman CK, Ravetch JV, Waldmann TA. Effective therapy for a murine model of adult T-cell leukemia with the humanized anti-CD52 monoclonal antibody, Campath-1H. Cancer Res. 2003 Oct 01; 63(19):6453-7.
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Friend PJ, Rebello P, Oliveira D, Manna V, Cobbold SP, Hale G, Jamieson NV, Jamieson I, Calne RY, Harris DT, et al. Successful treatment of renal allograft rejection with a humanized antilymphocyte monoclonal antibody. Transplant Proc. 1995 Feb; 27(1):869-70.