"Centromere Protein A" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 17 kDa, centromeric, poly(ADP)-ribose binding protein that is structurally similar to HISTONE H3 and localizes to NUCLEOSOMES within the CENTROMERE; specifically within the region that binds KINETOCHORES, where it replaces histone H3. It plays a critical role in recruiting kinetochore proteins and progression through MITOSIS, chromosome segregation, and CYTOKINESIS. It also binds sera from patients with some scleroderma-like AUTOIMMUNE DISEASES.
|Centromere Protein A
- Centromere Protein A
- CENPA Protein
- Centromere Protein 17K
- CENP-A Protein
- CENP A Protein
- Centromere Autoantigens 17K
- Autoantigens 17K, Centromere
Below are MeSH descriptors whose meaning is more general than "Centromere Protein A".
Below are MeSH descriptors whose meaning is more specific than "Centromere Protein A".
This graph shows the total number of publications written about "Centromere Protein A" by people in this website by year, and whether "Centromere Protein A" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.