TCF Transcription Factors

"TCF Transcription Factors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A family of DNA-binding proteins that are primarily expressed in T-LYMPHOCYTES. They interact with BETA CATENIN and serve as transcriptional activators and repressors in a variety of developmental processes.

Descriptor ID	D051820
MeSH Number(s)	D12.776.260.730 D12.776.660.235.400.800 D12.776.664.235.400.800 D12.776.930.875
Concept/Terms	TCF Transcription Factors TCF Transcription Factors Transcription Factors, TCF Lymphoid Enhancer Factors T-Cell Factors T Cell Factors LEF Transcription Factors Transcription Factors, LEF

Below are MeSH descriptors whose meaning is more general than "TCF Transcription Factors".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
DNA-Binding Proteins [D12.776.260]
TCF Transcription Factors [D12.776.260.730]
Nuclear Proteins [D12.776.660]
Chromosomal Proteins, Non-Histone [D12.776.660.235]
High Mobility Group Proteins [D12.776.660.235.400]
TCF Transcription Factors [D12.776.660.235.400.800]
Nucleoproteins [D12.776.664]
Chromosomal Proteins, Non-Histone [D12.776.664.235]
High Mobility Group Proteins [D12.776.664.235.400]
TCF Transcription Factors [D12.776.664.235.400.800]
Transcription Factors [D12.776.930]
TCF Transcription Factors [D12.776.930.875]

Below are MeSH descriptors whose meaning is related to "TCF Transcription Factors".

Below are MeSH descriptors whose meaning is more specific than "TCF Transcription Factors".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "TCF Transcription Factors" by people in this website by year, and whether "TCF Transcription Factors" was a major or minor topic of these publications.

Bar chart showing 10 publications over 10 distinct years, with a maximum of 1 publications in 2001 and 2003 and 2006 and 2007 and 2008 and 2009 and 2010 and 2011 and 2020 and 2021

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2001	0	1	1
2003	0	1	1
2006	1	0	1
2007	0	1	1
2008	0	1	1
2009	1	0	1
2010	0	1	1
2011	1	0	1
2020	1	0	1
2021	0	1	1

Below are the most recent publications written about "TCF Transcription Factors" by people in Profiles.

Rappaport JA, Entezari AA, Caspi A, Caksa S, Jhaveri AV, Stanek TJ, Ertel A, Kupper J, Fortina PM, McMahon SB, Jaynes JB, Snook AE, Waldman SA. A ?-Catenin-TCF-Sensitive Locus Control Region Mediates GUCY2C Ligand Loss in Colorectal Cancer. Cell Mol Gastroenterol Hepatol. 2022; 13(4):1276-1296.

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Blomain ES, Rappaport JA, Pattison AM, Bashir B, Caparosa E, Stem J, Snook AE, Waldman SA. APC-?-catenin-TCF signaling silences the intestinal guanylin-GUCY2C tumor suppressor axis. Cancer Biol Ther. 2020 05 03; 21(5):441-451.

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McCarthy TL, Kallen CB, Centrella M. ?-Catenin independent cross-control between the estradiol and Wnt pathways in osteoblasts. Gene. 2011 Jun 15; 479(1-2):16-28.

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Huang BL, Brugger SM, Lyons KM. Stage-specific control of connective tissue growth factor (CTGF/CCN2) expression in chondrocytes by Sox9 and beta-catenin. J Biol Chem. 2010 Sep 03; 285(36):27702-12.

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Boman B, Kopelovich L, Siracusa LD, Zhang T, Henderson K, Cofer Z, Buchberg AM, Fields JZ, Otevrel T. A Tcf4-GFP reporter mouse model for monitoring effects of Apc mutations during intestinal tumorigenesis. Mol Carcinog. 2009 Sep; 48(9):821-31.

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De Falco G, Leucci E, Onnis A, Bellan C, Tigli C, Wirths S, Cerino G, Cocco M, Crupi D, De Luca A, Lanzavecchia A, Tosi P, Leoncini L, Giordano A. Cdk9/Cyclin T1 complex: a key player during the activation/differentiation process of normal lymphoid B cells. J Cell Physiol. 2008 Apr; 215(1):276-82.

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Leucci E, De Falco G, Onnis A, Cerino G, Cocco M, Luzzi A, Crupi D, Tigli C, Bellan C, Tosi P, Leoncini L, Giordano A. The role of the Cdk9/Cyclin T1 complex in T cell differentiation. J Cell Physiol. 2007 Aug; 212(2):411-5.

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Toualbi K, G?ller MC, Mauriz JL, Labalette C, Buendia MA, Mauviel A, Bernuau D. Physical and functional cooperation between AP-1 and beta-catenin for the regulation of TCF-dependent genes. Oncogene. 2007 May 24; 26(24):3492-502.

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Seki Y, Yamamoto H, Ngan CY, Yasui M, Tomita N, Kitani K, Takemasa I, Ikeda M, Sekimoto M, Matsuura N, Albanese C, Kaneda Y, Pestell RG, Monden M. Construction of a novel DNA decoy that inhibits the oncogenic beta-catenin/T-cell factor pathway. Mol Cancer Ther. 2006 Apr; 5(4):985-94.

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Sotgia F, Williams TM, Cohen AW, Minetti C, Pestell RG, Lisanti MP. Caveolin-1-deficient mice have an increased mammary stem cell population with upregulation of Wnt/beta-catenin signaling. Cell Cycle. 2005 Dec; 4(12):1808-16.

View in: PubMed

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