"Carbonic Anhydrase IX" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A carbonic anhydrase and transmembrane protein that consists of an N-terminal PROTEOGLYCAN-like domain, a catalytic region, a single-pass transmembrane domain, and a short intracellular tail. It functions as a dimer and is expressed primarily by cells of the GASTROINTESTINAL TRACT; BILE DUCT EPITHELIUM; and GALL BLADDER. It is expressed at high levels in many solid tumors, especially CLEAR CELL RENAL CARCINOMA, in response to CELL HYPOXIA.
Descriptor ID |
D000071231
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MeSH Number(s) |
D08.811.520.241.300.150.450 D12.776.543.178 D23.050.285.196
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Carbonic Anhydrase IX".
Below are MeSH descriptors whose meaning is more specific than "Carbonic Anhydrase IX".
This graph shows the total number of publications written about "Carbonic Anhydrase IX" by people in this website by year, and whether "Carbonic Anhydrase IX" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2009 | 0 | 1 | 1 |
2011 | 0 | 1 | 1 |
2016 | 0 | 1 | 1 |
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Below are the most recent publications written about "Carbonic Anhydrase IX" by people in Profiles.
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Knudsen ES, Balaji U, Freinkman E, McCue P, Witkiewicz AK. Unique metabolic features of pancreatic cancer stroma: relevance to the tumor compartment, prognosis, and invasive potential. Oncotarget. 2016 Nov 29; 7(48):78396-78411.
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Yopp AC, Schwartz LH, Kemeny N, Gultekin DH, G?nen M, Bamboat Z, Shia J, Haviland D, D'Angelica MI, Fong Y, DeMatteo RP, Allen PJ, Jarnagin WR. Antiangiogenic therapy for primary liver cancer: correlation of changes in dynamic contrast-enhanced magnetic resonance imaging with tissue hypoxia markers and clinical response. Ann Surg Oncol. 2011 Aug; 18(8):2192-9.
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Li Y, Wang H, Oosterwijk E, Selman Y, Mira JC, Medrano T, Shiverick KT, Frost SC. Antibody-specific detection of CAIX in breast and prostate cancers. Biochem Biophys Res Commun. 2009 Aug 28; 386(3):488-92.