ErbB Receptors

"ErbB Receptors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A family of structurally-related cell-surface receptors that signal through an intrinsic PROTEIN-TYROSINE KINASE. The receptors are activated upon binding of specific ligands which include EPIDERMAL GROWTH FACTORS, and NEUREGULINS.

Descriptor ID	D066246
MeSH Number(s)	D08.811.913.696.620.682.725.400.009 D12.776.543.750.630.009 D12.776.543.750.750.400.074
Concept/Terms	ErbB Receptors ErbB Receptors Receptors, ErbB Receptors, Epidermal Growth Factor-Urogastrone Receptors, Epidermal Growth Factor Urogastrone Receptors, Epidermal Growth Factor EGF Receptors Receptors, EGF Epidermal Growth Factor Receptor Family Proteins HER Family Receptors Family Receptors, HER Receptors, HER Family Erb-b2 Receptor Tyrosine Kinases Erb b2 Receptor Tyrosine Kinases

Below are MeSH descriptors whose meaning is more general than "ErbB Receptors".

Chemicals and Drugs [D]
Enzymes and Coenzymes [D08]
Enzymes [D08.811]
Transferases [D08.811.913]
Phosphotransferases [D08.811.913.696]
Phosphotransferases (Alcohol Group Acceptor) [D08.811.913.696.620]
Protein Kinases [D08.811.913.696.620.682]
Protein-Tyrosine Kinases [D08.811.913.696.620.682.725]
Receptor Protein-Tyrosine Kinases [D08.811.913.696.620.682.725.400]
ErbB Receptors [D08.811.913.696.620.682.725.400.009]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Membrane Proteins [D12.776.543]
Receptors, Cell Surface [D12.776.543.750]
Receptor Protein-Tyrosine Kinases [D12.776.543.750.630]
ErbB Receptors [D12.776.543.750.630.009]
Receptors, Peptide [D12.776.543.750.750]
Receptors, Growth Factor [D12.776.543.750.750.400]
ErbB Receptors [D12.776.543.750.750.400.074]

Below are MeSH descriptors whose meaning is related to "ErbB Receptors".

Below are MeSH descriptors whose meaning is more specific than "ErbB Receptors".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "ErbB Receptors" by people in this website by year, and whether "ErbB Receptors" was a major or minor topic of these publications.

Bar chart showing 121 publications over 27 distinct years, with a maximum of 11 publications in 2014

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1995	1	2	3
1996	2	2	4
1997	6	1	7
1999	1	0	1
2000	1	0	1
2002	2	1	3
2003	1	2	3
2004	2	0	2
2005	1	2	3
2006	2	3	5
2007	2	5	7
2008	5	5	10
2009	4	3	7
2010	3	4	7
2011	2	6	8
2012	7	2	9
2013	1	1	2
2014	5	6	11
2015	6	1	7
2016	2	1	3
2017	0	2	2
2018	0	4	4
2019	2	1	3
2020	0	2	2
2021	0	4	4
2022	0	2	2
2024	0	1	1

Below are the most recent publications written about "ErbB Receptors" by people in Profiles.

Chen MF, Song Z, Yu HA, Sequist LV, Lovly CM, Mitchell EP, Moscow JA, Gray RJ, Wang V, McShane LM, Rubinstein LV, Patton DR, Williams PM, Hamilton SR, Umemura Y, Tricoli JV, Conley BA, Arteaga CL, Harris LN, O'Dwyer PJ, Chen AP, Flaherty KT. Phase II Study of Osimertinib in Patients With Epidermal Growth Factor Receptor Mutations: Results From the NCI-MATCH ECOG-ACRIN (EAY131) Trial Subprotocol E. JCO Precis Oncol. 2024 Apr; 8:e2300454.

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Ventura E, Xie C, Buraschi S, Belfiore A, Iozzo RV, Giordano A, Morrione A. Complexity of progranulin mechanisms of action in mesothelioma. J Exp Clin Cancer Res. 2022 Dec 05; 41(1):333.

View in: PubMed
Reyes M, Taghvaei M, Yu S, Sathe A, Collopy S, Prashant GN, Evans JJ, Karsy M. Targeted Therapy in the Management of Modern Craniopharyngiomas. Front Biosci (Landmark Ed). 2022 04 20; 27(4):136.

View in: PubMed
Fisk JN, Mahal AR, Dornburg A, Gaffney SG, Aneja S, Contessa JN, Rimm D, Yu JB, Townsend JP. Premetastatic shifts of endogenous and exogenous mutational processes support consolidative therapy in EGFR-driven lung adenocarcinoma. Cancer Lett. 2022 02 01; 526:346-351.

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Srour AM, Panda SS, Mostafa A, Fayad W, El-Manawaty MA, A F Soliman A, Moatasim Y, El Taweel A, Abdelhameed MF, Bekheit MS, Ali MA, Girgis AS. Synthesis of aspirin-curcumin mimic conjugates of potential antitumor and anti-SARS-CoV-2 properties. Bioorg Chem. 2021 12; 117:105466.

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Chan GK, McGrath JA, Parsons M. Spatial activation of ezrin by epidermal growth factor receptor and focal adhesion kinase co-ordinates epithelial cell migration. Open Biol. 2021 08; 11(8):210166.

View in: PubMed
Liu X, Adorno-Cruz V, Chang YF, Jia Y, Kawaguchi M, Dashzeveg NK, Taftaf R, Ramos EK, Schuster EJ, El-Shennawy L, Patel D, Zhang Y, Cristofanilli M, Liu H. EGFR inhibition blocks cancer stem cell clustering and lung metastasis of triple negative breast cancer. Theranostics. 2021; 11(13):6632-6643.

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Cramer G, Lewis R, Gymarty A, Hagan S, Mickler M, Evans S, Punekar SR, Shuman L, Simone CB, Hahn SM, Busch TM, Fraker D, Cengel KA. Preclinical Evaluation of Cetuximab and Benzoporphyrin Derivative-Mediated Intraperitoneal Photodynamic Therapy in a Canine Model. Photochem Photobiol. 2020 05; 96(3):684-691.

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Zhang A, Duchatelet S, Lakdawala N, Tower RL, Diamond C, Marathe K, Hill I, Richard G, Diab Y, Kirkorian AY, Watanabe F, Siegel DH, Hovnanian A. Targeted Inhibition of the Epidermal Growth Factor Receptor and Mammalian Target of Rapamycin Signaling Pathways in Olmsted Syndrome. JAMA Dermatol. 2020 02 01; 156(2):196-200.

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Hayes DF. HER2 and Breast Cancer - A Phenomenal Success Story. N Engl J Med. 2019 09 26; 381(13):1284-1286.

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