von Willebrand Factor

"von Willebrand Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A high-molecular-weight plasma protein, produced by endothelial cells and megakaryocytes, that is part of the factor VIII/von Willebrand factor complex. The von Willebrand factor has receptors for collagen, platelets, and ristocetin activity as well as the immunologically distinct antigenic determinants. It functions in adhesion of platelets to collagen and hemostatic plug formation. The prolonged bleeding time in VON WILLEBRAND DISEASES is due to the deficiency of this factor.

Descriptor ID	D014841
MeSH Number(s)	D12.776.124.125.920 D23.119.985
Concept/Terms	von Willebrand Factor von Willebrand Factor Factor VIIIR-Ag Factor VIIIR Ag Factor VIIIR-RCo Factor VIIIR RCo Ristocetin-Willebrand Factor Ristocetin Willebrand Factor von Willebrand Protein Factor VIII-Related Antigen Factor VIII Related Antigen Ristocetin Cofactor Plasma Factor VIII Complex Plasma Factor VIII Complex

Below are MeSH descriptors whose meaning is more general than "von Willebrand Factor".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Blood Proteins [D12.776.124]
Blood Coagulation Factors [D12.776.124.125]
von Willebrand Factor [D12.776.124.125.920]
Biological Factors [D23]
Blood Coagulation Factors [D23.119]
von Willebrand Factor [D23.119.985]

Below are MeSH descriptors whose meaning is more specific than "von Willebrand Factor".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "von Willebrand Factor" by people in this website by year, and whether "von Willebrand Factor" was a major or minor topic of these publications.

Bar chart showing 24 publications over 13 distinct years, with a maximum of 4 publications in 2002 and 2009

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2002	0	4	4
2003	0	1	1
2005	0	1	1
2006	1	1	2
2007	2	0	2
2008	1	1	2
2009	3	1	4
2010	0	1	1
2014	1	0	1
2016	1	1	2
2017	0	1	1
2018	1	1	2
2021	0	1	1

Below are the most recent publications written about "von Willebrand Factor" by people in Profiles.

Pierce-Williams RAM, Makhamreh MM, Blakey-Cheung S, Gao Z, Al-Kouatly HB. Postpartum Hemorrhage in Patients with Type 1 von Willebrand Disease: A Systematic Review. Semin Thromb Hemost. 2022 Mar; 48(2):219-228.

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Verbree-Willemsen L, Zhang YN, Gijsberts CM, Schoneveld AH, Wang JW, Lam CSP, Vernooij F, Bots ML, Peelen LM, Grobbee DE, Raichlen JS, de Kleijn DPV. LDL extracellular vesicle coagulation protein levels change after initiation of statin therapy. Findings from the METEOR trial. Int J Cardiol. 2018 Nov 15; 271:247-253.

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Favaloro EJ, Bonar R, Hollestelle MJ, Jennings I, Mohammed S, Meijer P, Woods T, Meiring M. Differential sensitivity of von Willebrand factor activity assays to reduced VWF molecular weight forms: A large international cross-laboratory study. Thromb Res. 2018 06; 166:96-105.

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Badolia R, Kostyak JC, Dangelmaier C, Kunapuli SP. Syk Activity Is Dispensable for Platelet GP1b-IX-V Signaling. Int J Mol Sci. 2017 Jun 09; 18(6).

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Zhu S, Tomaiuolo M, Diamond SL. Minimum wound size for clotting: flowing blood coagulates on a single collagen fiber presenting tissue factor and von Willebrand factor. Integr Biol (Camb). 2016 08 08; 8(8):813-20.

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Flex A, Biscetti F, Iachininoto MG, Nuzzolo ER, Orlando N, Capodimonti S, Angelini F, Valentini CG, Bianchi M, Larocca LM, Martini M, Teofili L. Human cord blood endothelial progenitors promote post-ischemic angiogenesis in immunocompetent mouse model. Thromb Res. 2016 May; 141:106-11.

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Kornej J, Dinov B, Blann AD, Rolf S, Arya A, Schmidl J, Husser D, Hindricks G, Bollmann A, Lip GY. Effects of radiofrequency catheter ablation of atrial fibrillation on soluble P-selectin, von Willebrand factor and IL-6 in the peripheral and cardiac circulation. PLoS One. 2014; 9(11):e111760.

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Pacheco LD, Costantine MM, Saade GR, Mucowski S, Hankins GD, Sciscione AC. von Willebrand disease and pregnancy: a practical approach for the diagnosis and treatment. Am J Obstet Gynecol. 2010 Sep; 203(3):194-200.

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Zhang P, Baxter J, Vinod K, Tulenko TN, Di Muzio PJ. Endothelial differentiation of amniotic fluid-derived stem cells: synergism of biochemical and shear force stimuli. Stem Cells Dev. 2009 Nov; 18(9):1299-308.

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Sgueglia GA, Niccoli G, Spaziani C, Cosentino N, Russo E, Andreotti F, Lanza GA, Landolfi R, Crea F. Baseline von Willebrand factor plasma levels and no-reflow phenomenon after primary percutaneous coronary intervention for ST segment elevation myocardial infarction. Int J Cardiol. 2010 Nov 19; 145(2):230-232.

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