Ion Channel Gating

"Ion Channel Gating" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The opening and closing of ion channels due to a stimulus. The stimulus can be a change in membrane potential (voltage-gated), drugs or chemical transmitters (ligand-gated), or a mechanical deformation. Gating is thought to involve conformational changes of the ion channel which alters selective permeability.

Descriptor ID	D015640
MeSH Number(s)	G02.111.820.400 G04.835.400 G07.265.625
Concept/Terms	Ion Channel Gating Ion Channel Gating Gating, Ion Channel Gatings, Ion Channel Ion Channel Gatings

Below are MeSH descriptors whose meaning is more general than "Ion Channel Gating".

Biological Sciences [G]
Chemical Phenomena [G02]
Biochemical Phenomena [G02.111]
Signal Transduction [G02.111.820]
Ion Channel Gating [G02.111.820.400]
Cell Physiological Phenomena [G04]
Signal Transduction [G04.835]
Ion Channel Gating [G04.835.400]
Physiological Phenomena [G07]
Electrophysiological Phenomena [G07.265]
Ion Channel Gating [G07.265.625]

Below are MeSH descriptors whose meaning is more specific than "Ion Channel Gating".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Ion Channel Gating" by people in this website by year, and whether "Ion Channel Gating" was a major or minor topic of these publications.

Bar chart showing 77 publications over 23 distinct years, with a maximum of 6 publications in 2002 and 2006 and 2008

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1995	1	1	2
1996	1	3	4
1997	2	2	4
1998	2	1	3
1999	2	1	3
2000	1	3	4
2001	1	2	3
2002	5	1	6
2003	1	3	4
2004	1	1	2
2005	1	3	4
2006	2	4	6
2007	2	1	3
2008	4	2	6
2009	2	3	5
2010	2	3	5
2011	4	1	5
2012	1	0	1
2013	1	1	2
2014	0	1	1
2016	0	1	1
2017	1	1	2
2022	1	0	1

Below are the most recent publications written about "Ion Channel Gating" by people in Profiles.

Chi G, Liang Q, Sridhar A, Cowgill JB, Sader K, Radjainia M, Qian P, Castro-Hartmann P, Venkaya S, Singh NK, McKinley G, Fernandez-Cid A, Mukhopadhyay SMM, Burgess-Brown NA, Delemotte L, Covarrubias M, Dürr KL. Cryo-EM structure of the human Kv3.1 channel reveals gating control by the cytoplasmic T1 domain. Nat Commun. 2022 Jul 15; 13(1):4087.

View in: PubMed
Wu M, White HV, Boehm BA, Meriney CJ, Kerrigan K, Frasso M, Liang M, Gotway EM, Wilcox MR, Johnson JW, Wipf P, Meriney SD. New Cav2 calcium channel gating modifiers with agonist activity and therapeutic potential to treat neuromuscular disease. Neuropharmacology. 2018 03 15; 131:176-189.

View in: PubMed
Woll KA, Peng W, Liang Q, Zhi L, Jacobs JA, Maciunas L, Bhanu N, Garcia BA, Covarrubias M, Loll PJ, Dailey WP, Eckenhoff RG. Photoaffinity Ligand for the Inhalational Anesthetic Sevoflurane Allows Mechanistic Insight into Potassium Channel Modulation. ACS Chem Biol. 2017 05 19; 12(5):1353-1362.

View in: PubMed
Syeda R, Florendo MN, Cox CD, Kefauver JM, Santos JS, Martinac B, Patapoutian A. Piezo1 Channels Are Inherently Mechanosensitive. Cell Rep. 2016 11 08; 17(7):1739-1746.

View in: PubMed
Di Diego JM, Antzelevitch C. Acute myocardial ischemia: cellular mechanisms underlying ST segment elevation. J Electrocardiol. 2014 Jul-Aug; 47(4):486-90.

View in: PubMed
Alzayady KJ, Wagner LE, Chandrasekhar R, Monteagudo A, Godiska R, Tall GG, Joseph SK, Yule DI. Functional inositol 1,4,5-trisphosphate receptors assembled from concatenated homo- and heteromeric subunits. J Biol Chem. 2013 Oct 11; 288(41):29772-84.

View in: PubMed
Raba AE, Cordeiro JM, Antzelevitch C, Beaumont J. Extending the conditions of application of an inversion of the Hodgkin-Huxley gating model. Bull Math Biol. 2013 May; 75(5):752-73.

View in: PubMed
Ho C, Zhao J, Malinowski S, Chahine M, O'Leary ME. Differential expression of sodium channel ß subunits in dorsal root ganglion sensory neurons. J Biol Chem. 2012 Apr 27; 287(18):15044-53.

View in: PubMed
Tabak J, Tomaiuolo M, Gonzalez-Iglesias AE, Milescu LS, Bertram R. Fast-activating voltage- and calcium-dependent potassium (BK) conductance promotes bursting in pituitary cells: a dynamic clamp study. J Neurosci. 2011 Nov 16; 31(46):16855-63.

View in: PubMed
Pau VP, Smith FJ, Taylor AB, Parfenova LV, Samakai E, Callaghan MM, Abarca-Heidemann K, Hart PJ, Rothberg BS. Structure and function of multiple Ca2+-binding sites in a K+ channel regulator of K+ conductance (RCK) domain. Proc Natl Acad Sci U S A. 2011 Oct 25; 108(43):17684-9.

View in: PubMed

People

Explore

Similar Concepts

Top Journals

The Thomas Jefferson University web site, its contents and programs, is provided for informational and educational purposes only and is not intended as medical advice nor is it intended to create any physician-patient relationship. Please remember that this information should not substitute for a visit or a consultation with a health care provider. The views or opinions expressed in the resources provided do not necessarily reflect those of Thomas Jefferson University, Thomas Jefferson University Hospital, or the Jefferson Health System or staff.
Please read our Privacy Statement