Mechanotransduction, Cellular

"Mechanotransduction, Cellular" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The process by which cells convert mechanical stimuli into a chemical response. It can occur in both cells specialized for sensing mechanical cues such as MECHANORECEPTORS, and in parenchymal cells whose primary function is not mechanosensory.

Descriptor ID	D040542
MeSH Number(s)	G01.154.090.500 G02.111.820.580 G04.835.580
Concept/Terms	Mechanotransduction, Cellular Mechanotransduction, Cellular Signal Transduction, Mechanical Mechanical Signal Transduction Cellular Mechanotransduction Mechanosensory Transduction Transduction, Mechanosensory

Below are MeSH descriptors whose meaning is more general than "Mechanotransduction, Cellular".

Biological Sciences [G]
Physical Phenomena [G01]
Biophysical Phenomena [G01.154]
Biomechanical Phenomena [G01.154.090]
Mechanotransduction, Cellular [G01.154.090.500]
Chemical Phenomena [G02]
Biochemical Phenomena [G02.111]
Signal Transduction [G02.111.820]
Mechanotransduction, Cellular [G02.111.820.580]
Cell Physiological Phenomena [G04]
Signal Transduction [G04.835]
Mechanotransduction, Cellular [G04.835.580]

Below are MeSH descriptors whose meaning is related to "Mechanotransduction, Cellular".

Below are MeSH descriptors whose meaning is more specific than "Mechanotransduction, Cellular".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Mechanotransduction, Cellular" by people in this website by year, and whether "Mechanotransduction, Cellular" was a major or minor topic of these publications.

Bar chart showing 28 publications over 15 distinct years, with a maximum of 4 publications in 2016 and 2021

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2003	2	0	2
2004	1	0	1
2005	1	0	1
2006	1	0	1
2008	0	1	1
2010	0	2	2
2012	1	1	2
2013	0	2	2
2014	1	1	2
2015	1	0	1
2016	3	1	4
2019	1	1	2
2020	1	1	2
2021	3	1	4
2022	0	1	1

Below are the most recent publications written about "Mechanotransduction, Cellular" by people in Profiles.

Riaz M, Park J, Sewanan LR, Ren Y, Schwan J, Das SK, Pomianowski PT, Huang Y, Ellis MW, Luo J, Liu J, Song L, Chen IP, Qiu C, Yazawa M, Tellides G, Hwa J, Young LH, Yang L, Marboe CC, Jacoby DL, Campbell SG, Qyang Y. Muscle LIM Protein Force-Sensing Mediates Sarcomeric Biomechanical Signaling in Human Familial Hypertrophic Cardiomyopathy. Circulation. 2022 04 19; 145(16):1238-1253.

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Barrick SK, Greenberg MJ. Cardiac myosin contraction and mechanotransduction in health and disease. J Biol Chem. 2021 11; 297(5):101297.

View in: PubMed
Trompeter N, Gardinier JD, DeBarros V, Boggs M, Gangadharan V, Cain WJ, Hurd L, Duncan RL. Insulin-like growth factor-1 regulates the mechanosensitivity of chondrocytes by modulating TRPV4. Cell Calcium. 2021 11; 99:102467.

View in: PubMed
Terashvili M, Talluri B, Palangmonthip W, Iczkowski KA, Sanvanson P, Medda BK, Banerjee B, Cunningham CW, Sengupta JN. Peripheral antinociceptive effects of a bifunctional ? and d opioid receptor ligand in rat model of inflammatory bladder pain. Neuropharmacology. 2021 09 15; 196:108701.

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Pathak P, Blech-Hermoni Y, Subedi K, Mpamugo J, Obeng-Nyarko C, Ohman R, Molloy I, Kates M, Hale J, Stauffer S, Sharan SK, Mankodi A. Myopathy associated LDB3 mutation causes Z-disc disassembly and protein aggregation through PKCa and TSC2-mTOR downregulation. Commun Biol. 2021 03 19; 4(1):355.

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Chery DR, Han B, Zhou Y, Wang C, Adams SM, Chandrasekaran P, Kwok B, Heo SJ, Enomoto-Iwamoto M, Lu XL, Kong D, Iozzo RV, Birk DE, Mauck RL, Han L. Decorin regulates cartilage pericellular matrix micromechanobiology. Matrix Biol. 2021 02; 96:1-17.

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Zhao G, Kim EW, Jiang J, Bhoot C, Charles KR, Baek J, Mohan S, Adams JS, Tetradis S, Lyons KM. CCN1/Cyr61 Is Required in Osteoblasts for Responsiveness to the Anabolic Activity of PTH. J Bone Miner Res. 2020 11; 35(11):2289-2300.

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Wagner K, Girardo S, Goswami R, Rosso G, Ulbricht E, M?ller P, Soteriou D, Tr?ber N, Guck J. Colloidal crystals of compliant microgel beads to study cell migration and mechanosensitivity in 3D. Soft Matter. 2019 Dec 04; 15(47):9776-9787.

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Taubenberger AV, Girardo S, Tr?ber N, Fischer-Friedrich E, Kr?ter M, Wagner K, Kurth T, Richter I, Haller B, Binner M, Hahn D, Freudenberg U, Werner C, Guck J. 3D Microenvironment Stiffness Regulates Tumor Spheroid Growth and Mechanics via p21 and ROCK. Adv Biosyst. 2019 09; 3(9):e1900128.

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Pozzi A, Yurchenco PD, Iozzo RV. The nature and biology of basement membranes. Matrix Biol. 2017 01; 57-58:1-11.

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