Hepatocyte Growth Factor

"Hepatocyte Growth Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Multifunctional growth factor which regulates both cell growth and cell motility. It exerts a strong mitogenic effect on hepatocytes and primary epithelial cells. Its receptor is PROTO-ONCOGENE PROTEINS C-MET.

Descriptor ID	D017228
MeSH Number(s)	D12.644.276.374.420 D12.776.467.374.420 D23.529.374.420
Concept/Terms	Hepatocyte Growth Factor Hepatocyte Growth Factor Factor, Hepatocyte Growth Growth Factor, Hepatocyte Scatter Factor Factor, Scatter Hepatopoietin Hepatopoietin A

Below are MeSH descriptors whose meaning is more general than "Hepatocyte Growth Factor".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Intercellular Signaling Peptides and Proteins [D12.644.276]
Cytokines [D12.644.276.374]
Hepatocyte Growth Factor [D12.644.276.374.420]
Proteins [D12.776]
Intercellular Signaling Peptides and Proteins [D12.776.467]
Cytokines [D12.776.467.374]
Hepatocyte Growth Factor [D12.776.467.374.420]
Biological Factors [D23]
Intercellular Signaling Peptides and Proteins [D23.529]
Cytokines [D23.529.374]
Hepatocyte Growth Factor [D23.529.374.420]

Below are MeSH descriptors whose meaning is related to "Hepatocyte Growth Factor".

Below are MeSH descriptors whose meaning is more specific than "Hepatocyte Growth Factor".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Hepatocyte Growth Factor" by people in this website by year, and whether "Hepatocyte Growth Factor" was a major or minor topic of these publications.

Bar chart showing 16 publications over 12 distinct years, with a maximum of 3 publications in 2010

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2002	1	0	1
2003	1	0	1
2004	1	1	2
2005	1	0	1
2006	2	0	2
2009	0	1	1
2010	0	3	3
2012	0	1	1
2015	0	1	1
2016	1	0	1
2017	1	0	1
2018	0	1	1

Below are the most recent publications written about "Hepatocyte Growth Factor" by people in Profiles.

Kumar D, Yalamanchali S, New J, Parsel S, New N, Holcomb A, Gunewardena S, Tawfik O, Lominska C, Kimler BF, Anant S, Kakarala K, Tsue T, Shnayder Y, Sykes K, Padhye S, Thomas SM. Development and Characterization of an In Vitro Model for Radiation-Induced Fibrosis. Radiat Res. 2018 03; 189(3):326-336.

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Cheng H, Chua V, Liao C, Purwin TJ, Terai M, Kageyama K, Davies MA, Sato T, Aplin AE. Co-targeting HGF/cMET Signaling with MEK Inhibitors in Metastatic Uveal Melanoma. Mol Cancer Ther. 2017 Mar; 16(3):516-528.

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Huwe PJ, Xu Q, Shapovalov MV, Modi V, Andrake MD, Dunbrack RL. Biological function derived from predicted structures in CASP11. Proteins. 2016 Sep; 84 Suppl 1:370-91.

View in: PubMed
Hamilton KE, Chatterji P, Lundsmith ET, Andres SF, Giroux V, Hicks PD, Noubissi FK, Spiegelman VS, Rustgi AK. Loss of Stromal IMP1 Promotes a Tumorigenic Microenvironment in the Colon. Mol Cancer Res. 2015 Nov; 13(11):1478-86.

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Moskowitz HS, Gooding WE, Thomas SM, Freilino ML, Gross N, Argiris A, Grandis JR, Ferris RL. Serum biomarker modulation following molecular targeting of epidermal growth factor and cyclooxygenase pathways: a pilot randomized trial in head and neck cancer. Oral Oncol. 2012 Nov; 48(11):1136-45.

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DeAngelis T, Morrione A, Baserga R. Mutual interaction and reciprocal down-regulation between c-met and insulin receptor substrate-1. J Cell Physiol. 2010 Sep; 224(3):658-63.

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Ding W, You H, Dang H, LeBlanc F, Galicia V, Lu SC, Stiles B, Rountree CB. Epithelial-to-mesenchymal transition of murine liver tumor cells promotes invasion. Hepatology. 2010 Sep; 52(3):945-53.

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Fitzpatrick JR, Frederick JR, McCormick RC, Harris DA, Kim AY, Muenzer JR, Gambogi AJ, Liu JP, Paulson EC, Woo YJ. Tissue-engineered pro-angiogenic fibroblast scaffold improves myocardial perfusion and function and limits ventricular remodeling after infarction. J Thorac Cardiovasc Surg. 2010 Sep; 140(3):667-76.

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Zhang P, Baxter J, Vinod K, Tulenko TN, Di Muzio PJ. Endothelial differentiation of amniotic fluid-derived stem cells: synergism of biochemical and shear force stimuli. Stem Cells Dev. 2009 Nov; 18(9):1299-308.

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Tate A, Isotani S, Bradley MJ, Sikes RA, Davis R, Chung LW, Edlund M. Met-Independent Hepatocyte Growth Factor-mediated regulation of cell adhesion in human prostate cancer cells. BMC Cancer. 2006; 6:197.

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