Receptors, Cytoplasmic and Nuclear

"Receptors, Cytoplasmic and Nuclear" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

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Intracellular receptors that can be found in the cytoplasm or in the nucleus. They bind to extracellular signaling molecules that migrate through or are transported across the CELL MEMBRANE. Many members of this class of receptors occur in the cytoplasm and are transported to the CELL NUCLEUS upon ligand-binding where they signal via DNA-binding and transcription regulation. Also included in this category are receptors found on INTRACELLULAR MEMBRANES that act via mechanisms similar to CELL SURFACE RECEPTORS.

Descriptor ID	D018160
MeSH Number(s)	D12.776.826
Concept/Terms	Receptors, Cytoplasmic and Nuclear Receptors, Cytoplasmic and Nuclear Receptors, Cytosol and Nuclear Cytosolic and Nuclear Receptors Receptors, Nuclear and Cytoplasmic Cytoplasmic and Nuclear Receptors Cytosol and Nuclear Receptors Nuclear and Cytoplasmic Receptors Receptors, Cytosolic and Nuclear Receptors, Nuclear Receptors, Nuclear Nuclear Receptors Receptors, Cytoplasmic Receptors, Cytoplasmic Cytoplasmic Receptors Receptors, Intracellular Membrane Receptors, Intracellular Membrane Membrane Receptors, Intracellular Intracellular Membrane Receptors Hormone Receptors, Cytoplasmic Hormone Receptors, Cytoplasmic Receptors, Cytoplasmic Hormone Cytoplasmic Hormone Receptors Hormone Receptors, Nuclear Hormone Receptors, Nuclear Receptors, Nuclear Hormone Nuclear Hormone Receptors

Below are MeSH descriptors whose meaning is more general than "Receptors, Cytoplasmic and Nuclear".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Receptors, Cytoplasmic and Nuclear [D12.776.826]

Below are MeSH descriptors whose meaning is related to "Receptors, Cytoplasmic and Nuclear".

Below are MeSH descriptors whose meaning is more specific than "Receptors, Cytoplasmic and Nuclear".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Receptors, Cytoplasmic and Nuclear" by people in this website by year, and whether "Receptors, Cytoplasmic and Nuclear" was a major or minor topic of these publications.

Bar chart showing 51 publications over 13 distinct years, with a maximum of 13 publications in 2004

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2001	1	0	1
2002	1	1	2
2003	7	1	8
2004	8	5	13
2005	3	0	3
2006	3	3	6
2007	5	1	6
2008	2	0	2
2009	1	1	2
2010	2	2	4
2011	1	1	2
2015	0	1	1
2021	0	1	1

Below are the most recent publications written about "Receptors, Cytoplasmic and Nuclear" by people in Profiles.

Alexander SP, Fabbro D, Kelly E, Mathie A, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Pawson AJ, Southan C, Davies JA, Beuve A, Brouckaert P, Bryant C, Burnett JC, Farndale RW, Friebe A, Garthwaite J, Hobbs AJ, Jarvis GE, Kuhn M, MacEwan D, Monie TP, Papapetropoulos A, Potter LR, Schmidt HHHW, Szabo C, Waldman SA. THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Catalytic receptors. Br J Pharmacol. 2021 Oct; 178 Suppl 1:S264-S312.

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Duker AL, Eldridge G, Braverman NE, Bober MB. Congenital heart defects common in rhizomelic chondrodysplasia punctata. Am J Med Genet A. 2016 Jan; 170A(1):270-2.

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Hyslop T, Weinberg DS, Schulz S, Barkun A, Waldman SA. Occult tumor burden contributes to racial disparities in stage-specific colorectal cancer outcomes. Cancer. 2012 May 1; 118(9):2532-40.

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Wang C, Powell M, Tian L, Pestell RG. Analysis of nuclear receptor acetylation. Methods Mol Biol. 2011; 776:169-81.

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Wang C, Tian L, Popov VM, Pestell RG. Acetylation and nuclear receptor action. J Steroid Biochem Mol Biol. 2011 Feb; 123(3-5):91-100.

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Lott K, Cingolani G. The importin ß binding domain as a master regulator of nucleocytoplasmic transport. Biochim Biophys Acta. 2011 Sep; 1813(9):1578-92.

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Bhardwaj A, Cingolani G. Conformational selection in the recognition of the snurportin importin beta binding domain by importin beta. Biochemistry. 2010 Jun 22; 49(24):5042-7.

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Lott K, Bhardwaj A, Mitrousis G, Pante N, Cingolani G. The importin beta binding domain modulates the avidity of importin beta for the nuclear pore complex. J Biol Chem. 2010 Apr 30; 285(18):13769-80.

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Dreieicher E, Beck KF, Lazaroski S, Boosen M, Tsalastra-Greul W, Beck M, Fleming I, Schaefer L, Pfeilschifter J. Nitric oxide inhibits glomerular TGF-beta signaling via SMOC-1. J Am Soc Nephrol. 2009 Sep; 20(9):1963-74.

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Debler EW, Blobel G, Hoelz A. Nuclear transport comes full circle. Nat Struct Mol Biol. 2009 May; 16(5):457-9.

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