"Frameshifting, Ribosomal" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A directed change in translational READING FRAMES that allows the production of a single protein from two or more OVERLAPPING GENES. The process is programmed by the nucleotide sequence of the MRNA and is sometimes also affected by the secondary or tertiary mRNA structure. It has been described mainly in VIRUSES (especially RETROVIRUSES); RETROTRANSPOSONS; and bacterial insertion elements but also in some cellular genes.
| Descriptor ID |
D018965
|
| MeSH Number(s) |
G02.111.660.871.200 G03.734.871.200 G05.308.215
|
| Concept/Terms |
Frameshifting, Ribosomal- Frameshifting, Ribosomal
- Ribosomal Frame Shift
- Frame Shift, Ribosomal
- Frame Shifts, Ribosomal
- Ribosomal Frame Shifts
- Frameshifting, Translational
- Translational Frameshifting
- Ribosomal Frameshifting
- Ribosomal Frameshift
- Frameshift, Ribosomal
- Frameshifts, Ribosomal
- Ribosomal Frameshifts
- Ribosomal Frame Shifting
- Frame Shifting, Ribosomal
|
Below are MeSH descriptors whose meaning is more general than "Frameshifting, Ribosomal".
Below are MeSH descriptors whose meaning is more specific than "Frameshifting, Ribosomal".
This graph shows the total number of publications written about "Frameshifting, Ribosomal" by people in this website by year, and whether "Frameshifting, Ribosomal" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 1 | 0 | 1 |
| 2008 | 1 | 0 | 1 |
| 2009 | 1 | 0 | 1 |
| 2010 | 2 | 0 | 2 |
| 2021 | 2 | 0 | 2 |
To return to the timeline,
click here.
Below are the most recent publications written about "Frameshifting, Ribosomal" by people in Profiles.
-
Masuda I, Hwang JY, Christian T, Maharjan S, Mohammad F, Gamper H, Buskirk AR, Hou YM. Loss of N1-methylation of G37 in tRNA induces ribosome stalling and reprograms gene expression. Elife. 2021 08 12; 10.
-
Demo G, Gamper HB, Loveland AB, Masuda I, Carbone CE, Svidritskiy E, Hou YM, Korostelev AA. Structural basis for +1 ribosomal frameshifting during EF-G-catalyzed translocation. Nat Commun. 2021 07 30; 12(1):4644.
-
Liao PY, Choi YS, Dinman JD, Lee KH. The many paths to frameshifting: kinetic modelling and analysis of the effects of different elongation steps on programmed -1 ribosomal frameshifting. Nucleic Acids Res. 2011 Jan; 39(1):300-12.
-
Masuda I, Matsuzaki M, Kita K. Extensive frameshift at all AGG and CCC codons in the mitochondrial cytochrome c oxidase subunit 1 gene of Perkinsus marinus (Alveolata; Dinoflagellata). Nucleic Acids Res. 2010 Oct; 38(18):6186-94.
-
Liao PY, Choi YS, Lee KH. FSscan: a mechanism-based program to identify +1 ribosomal frameshift hotspots. Nucleic Acids Res. 2009 Nov; 37(21):7302-11.
-
Olia AS, Cingolani G. A shifty stop for a hairy tail. Mol Microbiol. 2008 Nov; 70(3):549-53.
-
Zook MB, Howard MT, Sinnathamby G, Atkins JF, Eisenlohr LC. Epitopes derived by incidental translational frameshifting give rise to a protective CTL response. J Immunol. 2006 Jun 1; 176(11):6928-34.