"Myosin Light Chains" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The smaller subunits of MYOSINS that bind near the head groups of MYOSIN HEAVY CHAINS. The myosin light chains have a molecular weight of about 20 KDa and there are usually one essential and one regulatory pair of light chains associated with each heavy chain. Many myosin light chains that bind calcium are considered "calmodulin-like" proteins.
| Descriptor ID |
D018994
|
| MeSH Number(s) |
D05.750.078.730.475.200 D12.776.157.125.475 D12.776.210.500.600.200 D12.776.220.525.475.200
|
| Concept/Terms |
Myosin Light Chains- Myosin Light Chains
- Light Chains, Myosin
- Myosin Light Chain
- Light Chain, Myosin
|
Below are MeSH descriptors whose meaning is more general than "Myosin Light Chains".
Below are MeSH descriptors whose meaning is more specific than "Myosin Light Chains".
This graph shows the total number of publications written about "Myosin Light Chains" by people in this website by year, and whether "Myosin Light Chains" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 0 | 1 |
| 2002 | 0 | 2 | 2 |
| 2003 | 0 | 4 | 4 |
| 2004 | 0 | 2 | 2 |
| 2005 | 0 | 1 | 1 |
| 2006 | 1 | 1 | 2 |
| 2007 | 0 | 1 | 1 |
| 2008 | 1 | 0 | 1 |
| 2009 | 2 | 0 | 2 |
| 2010 | 3 | 2 | 5 |
| 2011 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Myosin Light Chains" by people in Profiles.
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Kitazawa T, Matsui T, Katsuki S, Goto A, Akagi K, Hatano N, Tokumitsu H, Takeya K, Eto M. A temporal Ca2+ desensitization of myosin light chain kinase in phasic smooth muscles induced by CaMKKß/PP2A pathways. Am J Physiol Cell Physiol. 2021 09 01; 321(3):C549-C558.
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Wilson AL, Schrecengost RS, Guerrero MS, Thomas KS, Bouton AH. Breast cancer antiestrogen resistance 3 (BCAR3) promotes cell motility by regulating actin cytoskeletal and adhesion remodeling in invasive breast cancer cells. PLoS One. 2013; 8(6):e65678.
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Khromov AS, Momotani K, Jin L, Artamonov MV, Shannon J, Eto M, Somlyo AV. Molecular mechanism of telokin-mediated disinhibition of myosin light chain phosphatase and cAMP/cGMP-induced relaxation of gastrointestinal smooth muscle. J Biol Chem. 2012 Jun 15; 287(25):20975-85.
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Butler TM, Siegman MJ. A force-activated kinase in a catch smooth muscle. J Muscle Res Cell Motil. 2011 Mar; 31(5-6):349-58.
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Gupta S, Hudak J, Killeen E, Larson JE, Cohen JC. Transient in utero nicotine exposure stimulates mechanosensory-dependent lung development. Exp Lung Res. 2010 Oct; 36(8):491-8.
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Jalagadugula G, Mao G, Kaur G, Goldfinger LE, Dhanasekaran DN, Rao AK. Regulation of platelet myosin light chain (MYL9) by RUNX1: implications for thrombocytopenia and platelet dysfunction in RUNX1 haplodeficiency. Blood. 2010 Dec 23; 116(26):6037-45.
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Greenberg MJ, Kazmierczak K, Szczesna-Cordary D, Moore JR. Cardiomyopathy-linked myosin regulatory light chain mutations disrupt myosin strain-dependent biochemistry. Proc Natl Acad Sci U S A. 2010 Oct 05; 107(40):17403-8.
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Minshall RD, Vandenbroucke EE, Holinstat M, Place AT, Tiruppathi C, Vogel SM, van Nieuw Amerongen GP, Mehta D, Malik AB. Role of protein kinase Czeta in thrombin-induced RhoA activation and inter-endothelial gap formation of human dermal microvessel endothelial cell monolayers. Microvasc Res. 2010 Sep; 80(2):240-9.
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Greenberg MJ, Mealy TR, Jones M, Szczesna-Cordary D, Moore JR. The direct molecular effects of fatigue and myosin regulatory light chain phosphorylation on the actomyosin contractile apparatus. Am J Physiol Regul Integr Comp Physiol. 2010 Apr; 298(4):R989-96.
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Pant K, Watt J, Greenberg M, Jones M, Szczesna-Cordary D, Moore JR. Removal of the cardiac myosin regulatory light chain increases isometric force production. FASEB J. 2009 Oct; 23(10):3571-80.