"Chromosome Breakage" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A type of chromosomal aberration involving DNA BREAKS. Chromosome breakage can result in CHROMOSOMAL TRANSLOCATION; CHROMOSOME INVERSION; or SEQUENCE DELETION.
| Descriptor ID |
D019457
|
| MeSH Number(s) |
C23.550.210.170 G05.200.210.170 G05.365.590.175.175
|
| Concept/Terms |
Chromosome Breakage- Chromosome Breakage
- Breakage, Chromosome
- Breakages, Chromosome
- Chromosome Breakages
- Chromosomal Breakage
- Breakage, Chromosomal
- Breakages, Chromosomal
- Chromosomal Breakages
Chromosome Breaks- Chromosome Breaks
- Break, Chromosome
- Breaks, Chromosome
- Chromosome Break
- Chromosomal Breaks
- Break, Chromosomal
- Breaks, Chromosomal
- Chromosomal Break
|
Below are MeSH descriptors whose meaning is more general than "Chromosome Breakage".
Below are MeSH descriptors whose meaning is more specific than "Chromosome Breakage".
This graph shows the total number of publications written about "Chromosome Breakage" by people in this website by year, and whether "Chromosome Breakage" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 1999 | 0 | 1 | 1 |
| 2000 | 1 | 0 | 1 |
| 2002 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2016 | 1 | 0 | 1 |
| 2020 | 1 | 1 | 2 |
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click here.
Below are the most recent publications written about "Chromosome Breakage" by people in Profiles.
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Serrano D, Cordero G, Kawamura R, Sverzhinsky A, Sarker M, Roy S, Malo C, Pascal JM, Marko JF, D'Amours D. The Smc5/6 Core Complex Is a Structure-Specific DNA Binding and Compacting Machine. Mol Cell. 2020 12 17; 80(6):1025-1038.e5.
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Carvajal-Garcia J, Cho JE, Carvajal-Garcia P, Feng W, Wood RD, Sekelsky J, Gupta GP, Roberts SA, Ramsden DA. Mechanistic basis for microhomology identification and genome scarring by polymerase theta. Proc Natl Acad Sci U S A. 2020 04 14; 117(15):8476-8485.
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Wyatt DW, Feng W, Conlin MP, Yousefzadeh MJ, Roberts SA, Mieczkowski P, Wood RD, Gupta GP, Ramsden DA. Essential Roles for Polymerase ?-Mediated End Joining in the Repair of Chromosome Breaks. Mol Cell. 2016 08 18; 63(4):662-673.
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Woodward KJ, Cundall M, Sperle K, Sistermans EA, Ross M, Howell G, Gribble SM, Burford DC, Carter NP, Hobson DL, Garbern JY, Kamholz J, Heng H, Hodes ME, Malcolm S, Hobson GM. Heterogeneous duplications in patients with Pelizaeus-Merzbacher disease suggest a mechanism of coupled homologous and nonhomologous recombination. Am J Hum Genet. 2005 Dec; 77(6):966-87.
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Turner BC, Ottey M, Zimonjic DB, Potoczek M, Hauck WW, Pequignot E, Keck-Waggoner CL, Sevignani C, Aldaz CM, McCue PA, Palazzo J, Huebner K, Popescu NC. The fragile histidine triad/common chromosome fragile site 3B locus and repair-deficient cancers. Cancer Res. 2002 Jul 15; 62(14):4054-60.
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Wachsberger PR, Iliakis G. Hyperthermia does not affect rejoining of DNA double-strand breaks in a cell-free assay. Int J Radiat Biol. 2000 Mar; 76(3):313-26.
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Hosler GA, Bash RO, Bai X, Jain V, Scheuermann RH. Development and validation of a quantitative polymerase chain reaction assay to evaluate minimal residual disease for T-cell acute lymphoblastic leukemia and follicular lymphoma. Am J Pathol. 1999 Apr; 154(4):1023-35.
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Kahlenberg MS, Stoler DL, Basik M, Petrelli NJ, Rodriguez-Bigas M, Anderson GR. p53 tumor suppressor gene status and the degree of genomic instability in sporadic colorectal cancers. J Natl Cancer Inst. 1996 Nov 20; 88(22):1665-70.