Pulmonary Surfactant-Associated Protein C
"Pulmonary Surfactant-Associated Protein C" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A pulmonary surfactant associated protein that plays a role in alveolar stability by lowering the surface tension at the air-liquid interface. It is a membrane-bound protein that constitutes 1-2% of the pulmonary surfactant mass. Pulmonary surfactant-associated protein C is one of the most hydrophobic peptides yet isolated and contains an alpha-helical domain with a central poly-valine segment that binds to phospholipid bilayers.
Descriptor ID |
D037721
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MeSH Number(s) |
D12.776.543.717 D12.776.816.750 D12.776.823.186
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Concept/Terms |
Pulmonary Surfactant-Associated Protein C- Pulmonary Surfactant-Associated Protein C
- Pulmonary Surfactant Associated Protein C
- Surfactant Polypeptide SP-C
- SP-C, Surfactant Polypeptide
- Surfactant Polypeptide SP C
- SP-C protein
- SP C protein
- Pulmonary Surfactant Protein C
- Pulmonary Surfactant-Associated Protein SP-C
- Pulmonary Surfactant Associated Protein SP C
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Below are MeSH descriptors whose meaning is more general than "Pulmonary Surfactant-Associated Protein C".
Below are MeSH descriptors whose meaning is more specific than "Pulmonary Surfactant-Associated Protein C".
This graph shows the total number of publications written about "Pulmonary Surfactant-Associated Protein C" by people in this website by year, and whether "Pulmonary Surfactant-Associated Protein C" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2005 | 0 | 1 | 1 |
2010 | 1 | 0 | 1 |
2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "Pulmonary Surfactant-Associated Protein C" by people in Profiles.
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Alapati D, Zacharias WJ, Hartman HA, Rossidis AC, Stratigis JD, Ahn NJ, Coons B, Zhou S, Li H, Singh K, Katzen J, Tomer Y, Chadwick AC, Musunuru K, Beers MF, Morrisey EE, Peranteau WH. In utero gene editing for monogenic lung disease. Sci Transl Med. 2019 04 17; 11(488).
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Poterjoy BS, Vibert Y, Sola-Visner M, McGowan J, Visner G, Nogee LM. Neonatal respiratory failure due to a novel mutation in the surfactant protein C gene. J Perinatol. 2010 Feb; 30(2):151-3.
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Chang JC, Summer R, Sun X, Fitzsimmons K, Fine A. Evidence that bone marrow cells do not contribute to the alveolar epithelium. Am J Respir Cell Mol Biol. 2005 Oct; 33(4):335-42.