Myosin-Light-Chain Phosphatase
"Myosin-Light-Chain Phosphatase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A phosphoprotein phosphatase that is specific for MYOSIN LIGHT CHAINS. It is composed of three subunits, which include a catalytic subunit, a myosin binding subunit, and a third subunit of unknown function.
Descriptor ID |
D043263
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MeSH Number(s) |
D08.811.277.352.650.625.475
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Concept/Terms |
Myosin-Light-Chain Phosphatase- Myosin-Light-Chain Phosphatase
- Phosphatase, Myosin-Light-Chain
- Myosin Light Chain Phosphatase
- Myosin Phosphatase
- Phosphatase, Myosin
- Calponin Phosphatase
- Phosphatase, Calponin
Smooth Muscle Phosphatase-II- Smooth Muscle Phosphatase-II
- Muscle Phosphatase-II, Smooth
- Phosphatase-II, Smooth Muscle
- Smooth Muscle Phosphatase II
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Below are MeSH descriptors whose meaning is more general than "Myosin-Light-Chain Phosphatase".
Below are MeSH descriptors whose meaning is more specific than "Myosin-Light-Chain Phosphatase".
This graph shows the total number of publications written about "Myosin-Light-Chain Phosphatase" by people in this website by year, and whether "Myosin-Light-Chain Phosphatase" was a major or minor topic of these publications.
To see the data from this visualization as text,
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Year | Major Topic | Minor Topic | Total |
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2001 | 0 | 1 | 1 |
2002 | 0 | 2 | 2 |
2003 | 0 | 5 | 5 |
2004 | 2 | 1 | 3 |
2005 | 0 | 3 | 3 |
2006 | 0 | 2 | 2 |
2007 | 1 | 0 | 1 |
2008 | 0 | 1 | 1 |
2009 | 3 | 2 | 5 |
2011 | 0 | 1 | 1 |
2012 | 1 | 1 | 2 |
2017 | 1 | 0 | 1 |
2022 | 0 | 1 | 1 |
2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Myosin-Light-Chain Phosphatase" by people in Profiles.
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Conaway S, Huang W, Hernandez-Lara MA, Kane MA, Penn RB, Deshpande DA. Molecular mechanism of bitter taste receptor agonist-mediated relaxation of airway smooth muscle. FASEB J. 2024 Jul 31; 38(14):e23842.
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Eto M, Katsuki S, Ohashi M, Miyagawa Y, Tanaka Y, Takeya K, Kitazawa T. Possible roles of N- and C-terminal unstructured tails of CPI-17 in regulating Ca2+ sensitization force of smooth muscle. J Smooth Muscle Res. 2022; 58(0):22-33.
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Filter JJ, Williams BC, Eto M, Shalloway D, Goldberg ML. Unfair competition governs the interaction of pCPI-17 with myosin phosphatase (PP1-MYPT1). Elife. 2017 04 07; 6.
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Kim JI, Urban M, Young GD, Eto M. Reciprocal regulation controlling the expression of CPI-17, a specific inhibitor protein for the myosin light chain phosphatase in vascular smooth muscle cells. Am J Physiol Cell Physiol. 2012 Jul 1; 303(1):C58-68.
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Rattan S, Singh J. RhoA/ROCK pathway is the major molecular determinant of basal tone in intact human internal anal sphincter. Am J Physiol Gastrointest Liver Physiol. 2012 Apr; 302(7):G664-75.
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Singh J, Maxwell PJ, Rattan S. Immunocytochemical evidence for PDBu-induced activation of RhoA/ROCK in human internal anal sphincter smooth muscle cells. Am J Physiol Gastrointest Liver Physiol. 2011 Aug; 301(2):G317-25.
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Eto M. Regulation of cellular protein phosphatase-1 (PP1) by phosphorylation of the CPI-17 family, C-kinase-activated PP1 inhibitors. J Biol Chem. 2009 Dec 18; 284(51):35273-7.
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Mori S, Iwaoka R, Eto M, Ohki SY. Solution structure of the inhibitory phosphorylation domain of myosin phosphatase targeting subunit 1. Proteins. 2009 Nov 15; 77(3):732-5.
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Khromov A, Choudhury N, Stevenson AS, Somlyo AV, Eto M. Phosphorylation-dependent autoinhibition of myosin light chain phosphatase accounts for Ca2+ sensitization force of smooth muscle contraction. J Biol Chem. 2009 Aug 7; 284(32):21569-79.
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Kitazawa T, Semba S, Huh YH, Kitazawa K, Eto M. Nitric oxide-induced biphasic mechanism of vascular relaxation via dephosphorylation of CPI-17 and MYPT1. J Physiol. 2009 Jul 15; 587(Pt 14):3587-603.