GTP-Binding Protein alpha Subunits, Gq-G11
"GTP-Binding Protein alpha Subunits, Gq-G11" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of heterotrimeric GTP-binding protein alpha subunits that activate TYPE C PHOSPHOLIPASES dependent signaling pathways. The Gq-G11 part of the name is also spelled Gq/G11.
| Descriptor ID |
D043802
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| MeSH Number(s) |
D08.811.277.040.330.300.200.100.300 D12.644.360.360.100.300 D12.776.157.325.332.100.300 D12.776.476.375.100.300 D12.776.543.325.100.300
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| Concept/Terms |
GTP-Binding Protein alpha Subunits, Gq-G11- GTP-Binding Protein alpha Subunits, Gq-G11
- GTP Binding Protein alpha Subunits, Gq G11
- Gq-G11 G-Proteins
- G-Proteins, Gq-G11
- Gq G11 G Proteins
- Gq-G11 G-Protein Family
- Family, Gq-G11 G-Protein
- G-Protein Family, Gq-G11
- Gq G11 G Protein Family
- G-Protein, Gq-G11 alpha Family
- G Protein, Gq G11 alpha Family
- G-Protein, Gq-G11
- G Protein, Gq G11
- Gq-G11 G-Protein
GTP-Binding Protein alpha Subunit, Gq- GTP-Binding Protein alpha Subunit, Gq
- GTP Binding Protein alpha Subunit, Gq
- G alpha q Protein
- Galphaq Protein
- G-Protein, Gq
- G Protein, Gq
- Gq G-Protein
- G-Protein, Gq alpha Family
- G Protein, Gq alpha Family
- G alpha Protein q
- Gq Protein
GTP-Binding Protein alpha Subunit, G11- GTP-Binding Protein alpha Subunit, G11
- GTP Binding Protein alpha Subunit, G11
- G alpha11 Protein
- Protein, G alpha11
- alpha11 Protein, G
- Galpha11 Protein
- Protein, Galpha11
- G-Protein, G11
- G Protein, G11
- G11 G-Protein
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Below are MeSH descriptors whose meaning is more general than "GTP-Binding Protein alpha Subunits, Gq-G11".
Below are MeSH descriptors whose meaning is more specific than "GTP-Binding Protein alpha Subunits, Gq-G11".
This graph shows the total number of publications written about "GTP-Binding Protein alpha Subunits, Gq-G11" by people in this website by year, and whether "GTP-Binding Protein alpha Subunits, Gq-G11" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2004 | 1 | 0 | 1 |
| 2005 | 1 | 1 | 2 |
| 2006 | 1 | 0 | 1 |
| 2008 | 1 | 0 | 1 |
| 2009 | 1 | 0 | 1 |
| 2010 | 1 | 0 | 1 |
| 2011 | 1 | 1 | 2 |
| 2017 | 0 | 1 | 1 |
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Below are the most recent publications written about "GTP-Binding Protein alpha Subunits, Gq-G11" by people in Profiles.
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Cheng H, Chua V, Liao C, Purwin TJ, Terai M, Kageyama K, Davies MA, Sato T, Aplin AE. Co-targeting HGF/cMET Signaling with MEK Inhibitors in Metastatic Uveal Melanoma. Mol Cancer Ther. 2017 Mar; 16(3):516-528.
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Li X, Chan TO, Myers V, Chowdhury I, Zhang XQ, Song J, Zhang J, Andrel J, Funakoshi H, Robbins J, Koch WJ, Hyslop T, Cheung JY, Feldman AM. Controlled and cardiac-restricted overexpression of the arginine vasopressin V1A receptor causes reversible left ventricular dysfunction through Gaq-mediated cell signaling. Circulation. 2011 Aug 2; 124(5):572-81.
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Bhavanasi D, Kim S, Goldfinger LE, Kunapuli SP. Protein kinase Cd mediates the activation of protein kinase D2 in platelets. Biochem Pharmacol. 2011 Oct 01; 82(7):720-7.
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Crouthamel M, Abankwa D, Zhang L, DiLizio C, Manning DR, Hancock JF, Wedegaertner PB. An N-terminal polybasic motif of Gaq is required for signaling and influences membrane nanodomain distribution. Mol Pharmacol. 2010 Oct; 78(4):767-77.
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Chahdi A, Sorokin A. The role of beta(1)Pix/caveolin-1 interaction in endothelin signaling through Galpha subunits. Biochem Biophys Res Commun. 2010 Jan 15; 391(3):1330-5.
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Crouthamel M, Thiyagarajan MM, Evanko DS, Wedegaertner PB. N-terminal polybasic motifs are required for plasma membrane localization of Galpha(s) and Galpha(q). Cell Signal. 2008 Oct; 20(10):1900-10.
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Kong KC, Billington CK, Gandhi U, Panettieri RA, Penn RB. Cooperative mitogenic signaling by G protein-coupled receptors and growth factors is dependent on G(q/11). FASEB J. 2006 Jul; 20(9):1558-60.
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McLaughlin JN, Shen L, Holinstat M, Brooks JD, Dibenedetto E, Hamm HE. Functional selectivity of G protein signaling by agonist peptides and thrombin for the protease-activated receptor-1. J Biol Chem. 2005 Jul 1; 280(26):25048-59.
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Evanko DS, Thiyagarajan MM, Takida S, Wedegaertner PB. Loss of association between activated Galpha q and Gbetagamma disrupts receptor-dependent and receptor-independent signaling. Cell Signal. 2005 Oct; 17(10):1218-28.
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Day PW, Tesmer JJ, Sterne-Marr R, Freeman LC, Benovic JL, Wedegaertner PB. Characterization of the GRK2 binding site of Galphaq. J Biol Chem. 2004 Dec 17; 279(51):53643-52.