Receptors, Proteinase-Activated
"Receptors, Proteinase-Activated" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A class of receptors that are activated by the action of PROTEINASES. The most notable examples are the THROMBIN RECEPTORS. The receptors contain cryptic ligands that are exposed upon the selective proteolysis of specific N-terminal cleavage sites.
| Descriptor ID |
D044462
|
| MeSH Number(s) |
D12.776.543.750.792
|
| Concept/Terms |
Receptors, Proteinase-Activated- Receptors, Proteinase-Activated
- Receptors, Proteinase Activated
- Protease-Activated Receptors
- Protease Activated Receptors
- Receptors, Protease-Activated
- Proteinase-Activated Receptors
- Proteinase Activated Receptors
- Endopeptidase-Activated Receptors
- Endopeptidase Activated Receptors
- Receptors, Endopeptidase-Activated
|
Below are MeSH descriptors whose meaning is more general than "Receptors, Proteinase-Activated".
Below are MeSH descriptors whose meaning is more specific than "Receptors, Proteinase-Activated".
This graph shows the total number of publications written about "Receptors, Proteinase-Activated" by people in this website by year, and whether "Receptors, Proteinase-Activated" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 1 | 0 | 1 |
| 2009 | 0 | 1 | 1 |
| 2010 | 1 | 0 | 1 |
| 2011 | 0 | 1 | 1 |
| 2023 | 1 | 0 | 1 |
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Below are the most recent publications written about "Receptors, Proteinase-Activated" by people in Profiles.
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Renna SA, McKenzie SE, Michael JV. Species Differences in Platelet Protease-Activated Receptors. Int J Mol Sci. 2023 May 05; 24(9).
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Apostolidis PA, Woulfe DS, Chavez M, Miller WM, Papoutsakis ET. Role of tumor suppressor p53 in megakaryopoiesis and platelet function. Exp Hematol. 2012 Feb; 40(2):131-42.e4.
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Holinstat M, Boutaud O, Apopa PL, Vesci J, Bala M, Oates JA, Hamm HE. Protease-activated receptor signaling in platelets activates cytosolic phospholipase A2a differently for cyclooxygenase-1 and 12-lipoxygenase catalysis. Arterioscler Thromb Vasc Biol. 2011 Feb; 31(2):435-42.
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Zhong Z, Ilieva H, Hallagan L, Bell R, Singh I, Paquette N, Thiyagarajan M, Deane R, Fernandez JA, Lane S, Zlokovic AB, Liu T, Griffin JH, Chow N, Castellino FJ, Stojanovic K, Cleveland DW, Zlokovic BV. Activated protein C therapy slows ALS-like disease in mice by transcriptionally inhibiting SOD1 in motor neurons and microglia cells. J Clin Invest. 2009 Nov; 119(11):3437-49.
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Dorsam RT, Tuluc M, Kunapuli SP. Role of protease-activated and ADP receptor subtypes in thrombin generation on human platelets. J Thromb Haemost. 2004 May; 2(5):804-12.