"Utrophin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An autosomally-encoded 376-kDa cytoskeletal protein that is similar in structure and function to DYSTROPHIN. It is a ubiquitously-expressed protein that plays a role in anchoring the CYTOSKELETON to the PLASMA MEMBRANE.
| Descriptor ID |
D049411
|
| MeSH Number(s) |
D12.776.220.987 D12.776.543.985
|
| Concept/Terms |
Utrophin- Utrophin
- UTRN Protein
- Dystrophin-Related Protein
- Dystrophin Related Protein
- Dystrophin-Related Protein 1
- Dystrophin Related Protein 1
|
Below are MeSH descriptors whose meaning is more general than "Utrophin".
Below are MeSH descriptors whose meaning is more specific than "Utrophin".
This graph shows the total number of publications written about "Utrophin" by people in this website by year, and whether "Utrophin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2011 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Utrophin" by people in Profiles.
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Song Y, Morales L, Malik AS, Mead AF, Greer CD, Mitchell MA, Petrov MT, Su LT, Choi ME, Rosenblum ST, Lu X, VanBelzen DJ, Krishnankutty RK, Balzer FJ, Loro E, French R, Propert KJ, Zhou S, Kozyak BW, Nghiem PP, Khurana TS, Kornegay JN, Stedman HH. Non-immunogenic utrophin gene therapy for the treatment of muscular dystrophy animal models. Nat Med. 2019 10; 25(10):1505-1511.
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Moorwood C, Lozynska O, Suri N, Napper AD, Diamond SL, Khurana TS. Drug discovery for Duchenne muscular dystrophy via utrophin promoter activation screening. PLoS One. 2011; 6(10):e26169.