"MutS Homolog 2 Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A highly conserved eukaryotic homolog of the MUTS DNA MISMATCH-BINDING PROTEIN. It plays an essential role in meiotic RECOMBINATION and DNA REPAIR of mismatched NUCLEOTIDES.
| Descriptor ID |
D051718
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| MeSH Number(s) |
D08.811.074.844.750 D08.811.277.040.025.292.750 D12.776.260.556.750 D12.776.624.664.700.130
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "MutS Homolog 2 Protein".
Below are MeSH descriptors whose meaning is more specific than "MutS Homolog 2 Protein".
This graph shows the total number of publications written about "MutS Homolog 2 Protein" by people in this website by year, and whether "MutS Homolog 2 Protein" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 1999 | 0 | 1 | 1 |
| 2002 | 0 | 3 | 3 |
| 2004 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2009 | 1 | 0 | 1 |
| 2011 | 1 | 0 | 1 |
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Below are the most recent publications written about "MutS Homolog 2 Protein" by people in Profiles.
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Hassen S, Boman BM, Ali N, Parker M, Somerman C, Ali-Khan Catts ZJ, Ali AA, Fields JZ. Detection of DNA mismatch repair proteins in fresh human blood lymphocytes--towards a novel method for hereditary non-polyposis colorectal cancer (Lynch syndrome) screening. J Exp Clin Cancer Res. 2011 Oct 21; 30:100.
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Manthey GM, Naik N, Bailis AM. Msh2 blocks an alternative mechanism for non-homologous tail removal during single-strand annealing in Saccharomyces cerevisiae. PLoS One. 2009 Oct 16; 4(10):e7488.
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Sheridan TB, Fenton H, Lewin MR, Burkart AL, Iacobuzio-Donahue CA, Frankel WL, Montgomery E. Sessile serrated adenomas with low- and high-grade dysplasia and early carcinomas: an immunohistochemical study of serrated lesions "caught in the act". Am J Clin Pathol. 2006 Oct; 126(4):564-71.
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Yang Q, Zhang R, Wang XW, Linke SP, Sengupta S, Hickson ID, Pedrazzi G, Perrera C, Stagljar I, Littman SJ, Modrich P, Harris CC. The mismatch DNA repair heterodimer, hMSH2/6, regulates BLM helicase. Oncogene. 2004 May 6; 23(21):3749-56.
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Alabyev B, Manser T. Bcl-2 rescues the germinal center response but does not alter the V gene somatic hypermutation spectrum in MSH2-deficient mice. J Immunol. 2002 Oct 1; 169(7):3819-24.
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Manthey GM, Bailis AM. Multiple pathways promote short-sequence recombination in Saccharomyces cerevisiae. Mol Cell Biol. 2002 Aug; 22(15):5347-56.
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Palazzo JP, Edmonston TB, Chaille-Arnold LM, Burkholder S. Invasive papillary adenocarcinoma of the colon. Hum Pathol. 2002 Mar; 33(3):372-5.
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Sevignani C, Cranston A, Iozzo RV, Fishel R, Calabretta B. Spontaneous and mutagen-induced transformation of primary cultures of Msh2-/- p53-/- colonocytes. Cancer Res. 1999 Dec 1; 59(23):5882-6.
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Negritto MT, Wu X, Kuo T, Chu S, Bailis AM. Influence of DNA sequence identity on efficiency of targeted gene replacement. Mol Cell Biol. 1997 Jan; 17(1):278-86.