Hypoxia-Inducible Factor 1

"Hypoxia-Inducible Factor 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A basic helix-loop-helix transcription factor that plays a role in APOPTOSIS. It is composed of two subunits: ARYL HYDROCARBON RECEPTOR NUCLEAR TRANSLOCATOR and HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT.

Descriptor ID	D051793
MeSH Number(s)	D12.776.260.103.625 D12.776.930.125.625
Concept/Terms	Hypoxia-Inducible Factor 1 Hypoxia-Inducible Factor 1 Hypoxia Inducible Factor 1

Below are MeSH descriptors whose meaning is more general than "Hypoxia-Inducible Factor 1".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
DNA-Binding Proteins [D12.776.260]
Basic Helix-Loop-Helix Transcription Factors [D12.776.260.103]
Hypoxia-Inducible Factor 1 [D12.776.260.103.625]
Transcription Factors [D12.776.930]
Basic Helix-Loop-Helix Transcription Factors [D12.776.930.125]
Hypoxia-Inducible Factor 1 [D12.776.930.125.625]

Below are MeSH descriptors whose meaning is related to "Hypoxia-Inducible Factor 1".

Below are MeSH descriptors whose meaning is more specific than "Hypoxia-Inducible Factor 1".

Hypoxia-Inducible Factor 1
Aryl Hydrocarbon Receptor Nuclear Translocator
Hypoxia-Inducible Factor 1, alpha Subunit

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Hypoxia-Inducible Factor 1" by people in this website by year, and whether "Hypoxia-Inducible Factor 1" was a major or minor topic of these publications.

Bar chart showing 13 publications over 9 distinct years, with a maximum of 3 publications in 2010

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2002	0	1	1
2004	0	1	1
2008	1	0	1
2009	0	2	2
2010	2	1	3
2011	0	1	1
2014	1	0	1
2017	1	0	1
2021	2	0	2

Below are the most recent publications written about "Hypoxia-Inducible Factor 1" by people in Profiles.

Silagi ES, Schipani E, Shapiro IM, Risbud MV. The role of HIF proteins in maintaining the metabolic health of the intervertebral disc. Nat Rev Rheumatol. 2021 07; 17(7):426-439.

View in: PubMed
Babapoor-Farrokhran S, Gill D, Alzubi J, Mainigi SK. Atrial fibrillation: the role of hypoxia-inducible factor-1-regulated cytokines. Mol Cell Biochem. 2021 Jun; 476(6):2283-2293.

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Bogdanovski DA, DiFazio LT, Bogdanovski AK, Cs?ka B, Jordan GB, Paul ER, Antonioli L, Pilip SA, Nemeth ZH. Hypoxia-inducible-factor-1 in trauma and critical care. J Crit Care. 2017 12; 42:207-212.

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Lee S, Goldfinger LE. RLIP76 regulates HIF-1 activity, VEGF expression and secretion in tumor cells, and secretome transactivation of endothelial cells. FASEB J. 2014 Sep; 28(9):4158-68.

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Liu LZ, Jiang Y, Carpenter RL, Jing Y, Peiper SC, Jiang BH. Role and mechanism of arsenic in regulating angiogenesis. PLoS One. 2011; 6(6):e20858.

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Kannan KB, Colorado I, Reino D, Palange D, Lu Q, Qin X, Abungu B, Watkins A, Caputo FJ, Xu DZ, Semenza GL, Deitch EA, Feinman R. Hypoxia-inducible factor plays a gut-injurious role in intestinal ischemia reperfusion injury. Am J Physiol Gastrointest Liver Physiol. 2011 May; 300(5):G853-61.

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Skubutyte R, Markova D, Freeman TA, Anderson DG, Dion AS, Williams CJ, Shapiro IM, Risbud MV. Hypoxia-inducible factor regulation of ANK expression in nucleus pulposus cells: possible implications in controlling dystrophic mineralization in the intervertebral disc. Arthritis Rheum. 2010 Sep; 62(9):2707-15.

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Pavlides S, Tsirigos A, Vera I, Flomenberg N, Frank PG, Casimiro MC, Wang C, Fortina P, Addya S, Pestell RG, Martinez-Outschoorn UE, Sotgia F, Lisanti MP. Loss of stromal caveolin-1 leads to oxidative stress, mimics hypoxia and drives inflammation in the tumor microenvironment, conferring the "reverse Warburg effect": a transcriptional informatics analysis with validation. Cell Cycle. 2010 Jun 1; 9(11):2201-19.

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Bohensky J, Terkhorn SP, Freeman TA, Adams CS, Garcia JA, Shapiro IM, Srinivas V. Regulation of autophagy in human and murine cartilage: hypoxia-inducible factor 2 suppresses chondrocyte autophagy. Arthritis Rheum. 2009 May; 60(5):1406-15.

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Srinivas V, Bohensky J, Zahm AM, Shapiro IM. Autophagy in mineralizing tissues: microenvironmental perspectives. Cell Cycle. 2009 Feb 1; 8(3):391-3.

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