Growth Differentiation Factor 15
"Growth Differentiation Factor 15" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A growth differentiation factor that is secreted in response to cell stress and in response to MACROPHAGE ACTIVATION. In addition growth differentiation factor 15 demonstrates a diverse array of biological properties including the induction of cartilage formation, the inhibition of hematopoietic progenitor proliferation, and the induction of neuronal migration.
| Descriptor ID |
D055436
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| MeSH Number(s) |
D12.644.276.374.305 D12.644.276.954.300.915 D12.776.467.374.305 D12.776.467.942.300.915 D23.529.374.305 D23.529.942.300.915
|
| Concept/Terms |
Growth Differentiation Factor 15- Growth Differentiation Factor 15
- Macrophage Inhibitory Cytokine 1
- Prostate Differentiation Factor
- Differentiation Factor, Prostate
- GDF-15
|
Below are MeSH descriptors whose meaning is more general than "Growth Differentiation Factor 15".
Below are MeSH descriptors whose meaning is more specific than "Growth Differentiation Factor 15".
This graph shows the total number of publications written about "Growth Differentiation Factor 15" by people in this website by year, and whether "Growth Differentiation Factor 15" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 2 | 2 |
| 2006 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2009 | 1 | 0 | 1 |
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Below are the most recent publications written about "Growth Differentiation Factor 15" by people in Profiles.
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Zimmers TA, Gutierrez JC, Koniaris LG. Loss of GDF-15 abolishes sulindac chemoprevention in the ApcMin/+ mouse model of intestinal cancer. J Cancer Res Clin Oncol. 2010 Apr; 136(4):571-6.
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Zimmers TA, Jin X, Gutierrez JC, Acosta C, McKillop IH, Pierce RH, Koniaris LG. Effect of in vivo loss of GDF-15 on hepatocellular carcinogenesis. J Cancer Res Clin Oncol. 2008 Jul; 134(7):753-9.
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Zimmers TA, Gutierrez JC, Koniaris LG. NAG-1/GDF-15: no evidence for an inhibitory role in colon cancer? Gastroenterology. 2007 Mar; 132(3):1204-5; author reply 1205.
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Koopmann J, Rosenzweig CN, Zhang Z, Canto MI, Brown DA, Hunter M, Yeo C, Chan DW, Breit SN, Goggins M. Serum markers in patients with resectable pancreatic adenocarcinoma: macrophage inhibitory cytokine 1 versus CA19-9. Clin Cancer Res. 2006 Jan 15; 12(2):442-6.
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Zimmers TA, Jin X, Hsiao EC, Perez EA, Pierce RH, Chavin KD, Koniaris LG. Growth differentiation factor-15: induction in liver injury through p53 and tumor necrosis factor-independent mechanisms. J Surg Res. 2006 Jan; 130(1):45-51.
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Zimmers TA, Jin X, Hsiao EC, McGrath SA, Esquela AF, Koniaris LG. Growth differentiation factor-15/macrophage inhibitory cytokine-1 induction after kidney and lung injury. Shock. 2005 Jun; 23(6):543-8.
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Koopmann J, Buckhaults P, Brown DA, Zahurak ML, Sato N, Fukushima N, Sokoll LJ, Chan DW, Yeo CJ, Hruban RH, Breit SN, Kinzler KW, Vogelstein B, Goggins M. Serum macrophage inhibitory cytokine 1 as a marker of pancreatic and other periampullary cancers. Clin Cancer Res. 2004 Apr 1; 10(7):2386-92.
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Koniaris LG. Induction of MIC-1/growth differentiation factor-15 following bile duct injury. J Gastrointest Surg. 2003 Nov; 7(7):901-5.