Bulbo-Spinal Atrophy, X-Linked
"Bulbo-Spinal Atrophy, X-Linked" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An X-linked recessive form of spinal muscular atrophy. It is due to a mutation of the gene encoding the ANDROGEN RECEPTOR.
| Descriptor ID |
D055534
|
| MeSH Number(s) |
C10.228.854.468.399 C10.574.500.175 C10.574.562.500.374 C10.668.467.500.186 C16.320.322.076
|
| Concept/Terms |
Bulbo-Spinal Atrophy, X-Linked- Bulbo-Spinal Atrophy, X-Linked
- Atrophies, X-Linked Bulbo-Spinal
- Atrophy, X-Linked Bulbo-Spinal
- Bulbo Spinal Atrophy, X Linked
- Bulbo-Spinal Atrophies, X-Linked
- X-Linked Bulbo-Spinal Atrophies
- Kennedy Disease
- Disease, Kennedy
- Kennedy Spinal and Bulbar Muscular Atrophy
- Kennedy Syndrome
- Syndrome, Kennedy
- X-Linked Bulbo-Spinal Atrophy
- X Linked Bulbo Spinal Atrophy
- X-linked Bulbospinal Muscular Atrophy
- X linked Bulbospinal Muscular Atrophy
- Kennedy's Disease
- Disease, Kennedy's
- Kennedys Disease
- X-Linked Spinal and Bulbar Muscular Atrophy
- X Linked Spinal and Bulbar Muscular Atrophy
- Bulbospinal Muscular Atrophy, X-linked
- Bulbospinal Muscular Atrophy, X linked
- Spinal And Bulbar Muscular Atrophy, X-Linked 1
- Spinal And Bulbar Muscular Atrophy, X Linked 1
|
Below are MeSH descriptors whose meaning is more general than "Bulbo-Spinal Atrophy, X-Linked".
- Diseases [C]
- Nervous System Diseases [C10]
- Central Nervous System Diseases [C10.228]
- Spinal Cord Diseases [C10.228.854]
- Muscular Atrophy, Spinal [C10.228.854.468]
- Bulbo-Spinal Atrophy, X-Linked [C10.228.854.468.399]
- Neurodegenerative Diseases [C10.574]
- Heredodegenerative Disorders, Nervous System [C10.574.500]
- Bulbo-Spinal Atrophy, X-Linked [C10.574.500.175]
- Motor Neuron Disease [C10.574.562]
- Muscular Atrophy, Spinal [C10.574.562.500]
- Bulbo-Spinal Atrophy, X-Linked [C10.574.562.500.374]
- Neuromuscular Diseases [C10.668]
- Motor Neuron Disease [C10.668.467]
- Muscular Atrophy, Spinal [C10.668.467.500]
- Bulbo-Spinal Atrophy, X-Linked [C10.668.467.500.186]
- Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16]
- Genetic Diseases, Inborn [C16.320]
- Genetic Diseases, X-Linked [C16.320.322]
- Bulbo-Spinal Atrophy, X-Linked [C16.320.322.076]
Below are MeSH descriptors whose meaning is more specific than "Bulbo-Spinal Atrophy, X-Linked".
This graph shows the total number of publications written about "Bulbo-Spinal Atrophy, X-Linked" by people in this website by year, and whether "Bulbo-Spinal Atrophy, X-Linked" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2009 | 1 | 0 | 1 |
| 2010 | 0 | 1 | 1 |
| 2011 | 1 | 0 | 1 |
| 2022 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Bulbo-Spinal Atrophy, X-Linked" by people in Profiles.
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Molotsky E, Liu Y, Lieberman AP, Merry DE. Neuromuscular junction pathology is correlated with differential motor unit vulnerability in spinal and bulbar muscular atrophy. Acta Neuropathol Commun. 2022 Jul 05; 10(1):97.
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Chevalier-Larsen ES, Merry DE. Testosterone treatment fails to accelerate disease in a transgenic mouse model of spinal and bulbar muscular atrophy. Dis Model Mech. 2012 Jan; 5(1):141-5.
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Orr CR, Montie HL, Liu Y, Bolzoni E, Jenkins SC, Wilson EM, Joseph JD, McDonnell DP, Merry DE. An interdomain interaction of the androgen receptor is required for its aggregation and toxicity in spinal and bulbar muscular atrophy. J Biol Chem. 2010 Nov 12; 285(46):35567-77.
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Montie HL, Merry DE. Autophagy and access: understanding the role of androgen receptor subcellular localization in SBMA. Autophagy. 2009 Nov; 5(8):1194-7.