"Biglycan" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A small leucine-rich proteoglycan found in a variety of tissues including CAPILLARY ENDOTHELIUM; SKELETAL MUSCLE; CARTILAGE; BONE; and TENDONS. The protein contains two glycosaminoglycan chains and is similar in structure to DECORIN.
| Descriptor ID |
D058578
|
| MeSH Number(s) |
D09.698.735.700.500 D12.776.395.650.750.562 D12.776.395.650.875.250 D12.776.860.300.806.500
|
| Concept/Terms |
Biglycan- Biglycan
- Proteoglycan S1
- Bone Proteoglycan I
|
Below are MeSH descriptors whose meaning is more general than "Biglycan".
Below are MeSH descriptors whose meaning is more specific than "Biglycan".
This graph shows the total number of publications written about "Biglycan" by people in this website by year, and whether "Biglycan" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 2 | 2 |
| 1998 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2004 | 0 | 3 | 3 |
| 2005 | 0 | 4 | 4 |
| 2006 | 0 | 2 | 2 |
| 2007 | 0 | 2 | 2 |
| 2008 | 0 | 1 | 1 |
| 2009 | 0 | 4 | 4 |
| 2010 | 1 | 0 | 1 |
| 2011 | 4 | 0 | 4 |
| 2012 | 3 | 1 | 4 |
| 2013 | 4 | 3 | 7 |
| 2014 | 2 | 0 | 2 |
| 2015 | 4 | 0 | 4 |
| 2016 | 4 | 0 | 4 |
| 2017 | 3 | 0 | 3 |
| 2018 | 1 | 1 | 2 |
| 2019 | 2 | 1 | 3 |
| 2021 | 2 | 4 | 6 |
| 2022 | 0 | 2 | 2 |
| 2023 | 0 | 1 | 1 |
| 2025 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Biglycan" by people in Profiles.
-
Hua R, Han Y, Ni Q, Fajardo RJ, Iozzo RV, Ahmed R, Nyman JS, Wang X, Jiang JX. Pivotal roles of biglycan and decorin in regulating bone mass, water retention, and bone toughness. Bone Res. 2025 Jan 02; 13(1):2.
-
Zeng-Brouwers J, Huber LS, Merline R, Trebicka J, Wygrecka M, Schaefer L. Evaluation of the In Vitro and In Vivo Effects of Biglycan in Innate Immunity. Methods Mol Biol. 2023; 2619:109-124.
-
Neill T, Xie C, Iozzo RV. Decorin evokes reversible mitochondrial depolarization in carcinoma and vascular endothelial cells. Am J Physiol Cell Physiol. 2022 11 01; 323(5):C1355-C1373.
-
Lee N, Shi L, Colon Caraballo M, Nallasamy S, Mahendroo M, Iozzo RV, Myers K. Mechanical Response of Mouse Cervices Lacking Decorin and Biglycan During Pregnancy. J Biomech Eng. 2022 06 01; 144(6).
-
Colon-Caraballo M, Lee N, Nallasamy S, Myers K, Hudson D, Iozzo RV, Mahendroo M. Novel regulatory roles of small leucine-rich proteoglycans in remodeling of the uterine cervix in pregnancy. Matrix Biol. 2022 01; 105:53-71.
-
Schaefer L, Dikic I. Autophagy: Instructions from the extracellular matrix. Matrix Biol. 2021 06; 100-101:1-8.
-
Schulz M, Diehl V, Trebicka J, Wygrecka M, Schaefer L. Biglycan: A regulator of hepatorenal inflammation and autophagy. Matrix Biol. 2021 06; 100-101:150-161.
-
Han B, Li Q, Wang C, Chandrasekaran P, Zhou Y, Qin L, Liu XS, Enomoto-Iwamoto M, Kong D, Iozzo RV, Birk DE, Han L. Differentiated activities of decorin and biglycan in the progression of post-traumatic osteoarthritis. Osteoarthritis Cartilage. 2021 08; 29(8):1181-1192.
-
Neill T, Kapoor A, Xie C, Buraschi S, Iozzo RV. A functional outside-in signaling network of proteoglycans and matrix molecules regulating autophagy. Matrix Biol. 2021 06; 100-101:118-149.
-
Pantham P, Armstrong DL, Bodnariuc J, Haupt O, Johnson AW, Underhill L, Iozzo RV, Lechner BE, Wildman DE. Transcriptomic profiling of fetal membranes of mice deficient in biglycan and decorin as a model of preterm birth?. Biol Reprod. 2021 03 11; 104(3):611-623.