"Biglycan" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A small leucine-rich proteoglycan found in a variety of tissues including CAPILLARY ENDOTHELIUM; SKELETAL MUSCLE; CARTILAGE; BONE; and TENDONS. The protein contains two glycosaminoglycan chains and is similar in structure to DECORIN.
| Descriptor ID |
D058578
|
| MeSH Number(s) |
D09.698.735.700.500 D12.776.395.650.750.562 D12.776.395.650.875.250 D12.776.860.300.806.500
|
| Concept/Terms |
Biglycan- Biglycan
- Proteoglycan S1
- Bone Proteoglycan I
|
Below are MeSH descriptors whose meaning is more general than "Biglycan".
Below are MeSH descriptors whose meaning is more specific than "Biglycan".
This graph shows the total number of publications written about "Biglycan" by people in this website by year, and whether "Biglycan" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 |
| 2004 | 0 | 3 | 3 |
| 2005 | 0 | 3 | 3 |
| 2006 | 0 | 2 | 2 |
| 2007 | 0 | 2 | 2 |
| 2008 | 0 | 1 | 1 |
| 2009 | 0 | 4 | 4 |
| 2010 | 1 | 0 | 1 |
| 2011 | 4 | 0 | 4 |
| 2012 | 2 | 1 | 3 |
| 2013 | 0 | 1 | 1 |
| 2016 | 2 | 0 | 2 |
| 2017 | 2 | 0 | 2 |
| 2018 | 1 | 1 | 2 |
| 2019 | 1 | 1 | 2 |
| 2021 | 0 | 2 | 2 |
| 2022 | 0 | 2 | 2 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Biglycan" by people in Profiles.
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Zeng-Brouwers J, Huber LS, Merline R, Trebicka J, Wygrecka M, Schaefer L. Evaluation of the In Vitro and In Vivo Effects of Biglycan in Innate Immunity. Methods Mol Biol. 2023; 2619:109-124.
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Neill T, Xie C, Iozzo RV. Decorin evokes reversible mitochondrial depolarization in carcinoma and vascular endothelial cells. Am J Physiol Cell Physiol. 2022 11 01; 323(5):C1355-C1373.
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Lee N, Shi L, Colon Caraballo M, Nallasamy S, Mahendroo M, Iozzo RV, Myers K. Mechanical Response of Mouse Cervices Lacking Decorin and Biglycan During Pregnancy. J Biomech Eng. 2022 Jun 01; 144(6).
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Schaefer L, Dikic I. Autophagy: Instructions from the extracellular matrix. Matrix Biol. 2021 06; 100-101:1-8.
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Schulz M, Diehl V, Trebicka J, Wygrecka M, Schaefer L. Biglycan: A regulator of hepatorenal inflammation and autophagy. Matrix Biol. 2021 06; 100-101:150-161.
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Roedig H, Damiescu R, Zeng-Brouwers J, Kutija I, Trebicka J, Wygrecka M, Schaefer L. Danger matrix molecules orchestrate CD14/CD44 signaling in cancer development. Semin Cancer Biol. 2020 05; 62:31-47.
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Roedig H, Nastase MV, Wygrecka M, Schaefer L. Breaking down chronic inflammatory diseases: the role of biglycan in promoting a switch between inflammation and autophagy. FEBS J. 2019 08; 286(15):2965-2979.
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Roedig H, Nastase MV, Frey H, Moreth K, Zeng-Brouwers J, Poluzzi C, Hsieh LT, Brandts C, Fulda S, Wygrecka M, Schaefer L. Biglycan is a new high-affinity ligand for CD14 in macrophages. Matrix Biol. 2019 04; 77:4-22.
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Nastase MV, Janicova A, Roedig H, Hsieh LT, Wygrecka M, Schaefer L. Small Leucine-Rich Proteoglycans in Renal Inflammation: Two Sides of the Coin. J Histochem Cytochem. 2018 04; 66(4):261-272.
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Nastase MV, Zeng-Brouwers J, Beckmann J, Tredup C, Christen U, Radeke HH, Wygrecka M, Schaefer L. Biglycan, a novel trigger of Th1 and Th17 cell recruitment into the kidney. Matrix Biol. 2018 08; 68-69:293-317.