Adenosine Diphosphate Ribose

"Adenosine Diphosphate Ribose" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

An ester formed between the aldehydic carbon of RIBOSE and the terminal phosphate of ADENOSINE DIPHOSPHATE. It is produced by the hydrolysis of nicotinamide-adenine dinucleotide (NAD) by a variety of enzymes, some of which transfer an ADP-ribosyl group to target proteins.

Descriptor ID	D000246
MeSH Number(s)	D03.633.100.759.646.138.124.070.125 D09.408.620.569.070.125 D13.695.667.138.124.070.125 D13.695.827.068.124.070.125 D13.695.827.708.070.125
Concept/Terms	Adenosine Diphosphate Ribose Adenosine Diphosphate Ribose Diphosphate Ribose, Adenosine Ribose, Adenosine Diphosphate ADP-Ribose ADP Ribose Ribose, ADP ADPribose Adenosine 5'-Diphosphoribose 5'-Diphosphoribose, Adenosine Adenosine 5' Diphosphoribose Adenosine Diphosphoribose Diphosphoribose, Adenosine

Below are MeSH descriptors whose meaning is more general than "Adenosine Diphosphate Ribose".

Chemicals and Drugs [D]
Heterocyclic Compounds [D03]
Heterocyclic Compounds, Fused-Ring [D03.633]
Heterocyclic Compounds, 2-Ring [D03.633.100]
Purines [D03.633.100.759]
Purine Nucleotides [D03.633.100.759.646]
Adenine Nucleotides [D03.633.100.759.646.138]
Adenosine Diphosphate [D03.633.100.759.646.138.124]
Adenosine Diphosphate Sugars [D03.633.100.759.646.138.124.070]
Adenosine Diphosphate Ribose [D03.633.100.759.646.138.124.070.125]
Carbohydrates [D09]
Glycosides [D09.408]
Nucleotides [D09.408.620]
Nucleoside Diphosphate Sugars [D09.408.620.569]
Adenosine Diphosphate Sugars [D09.408.620.569.070]
Adenosine Diphosphate Ribose [D09.408.620.569.070.125]
Nucleic Acids, Nucleotides, and Nucleosides [D13]
Nucleotides [D13.695]
Purine Nucleotides [D13.695.667]
Adenine Nucleotides [D13.695.667.138]
Adenosine Diphosphate [D13.695.667.138.124]
Adenosine Diphosphate Sugars [D13.695.667.138.124.070]
Adenosine Diphosphate Ribose [D13.695.667.138.124.070.125]
Ribonucleotides [D13.695.827]
Adenine Nucleotides [D13.695.827.068]
Adenosine Diphosphate [D13.695.827.068.124]
Adenosine Diphosphate Sugars [D13.695.827.068.124.070]
Adenosine Diphosphate Ribose [D13.695.827.068.124.070.125]
Nucleoside Diphosphate Sugars [D13.695.827.708]
Adenosine Diphosphate Sugars [D13.695.827.708.070]
Adenosine Diphosphate Ribose [D13.695.827.708.070.125]

Below are MeSH descriptors whose meaning is related to "Adenosine Diphosphate Ribose".

Below are MeSH descriptors whose meaning is more specific than "Adenosine Diphosphate Ribose".

Adenosine Diphosphate Ribose
Cyclic ADP-Ribose
O-Acetyl-ADP-Ribose

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Adenosine Diphosphate Ribose" by people in this website by year, and whether "Adenosine Diphosphate Ribose" was a major or minor topic of these publications.

Bar chart showing 12 publications over 9 distinct years, with a maximum of 2 publications in 2021 and 2022 and 2023

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2000	0	1	1
2001	0	1	1
2016	0	1	1
2018	0	1	1
2019	0	1	1
2021	1	1	2
2022	1	1	2
2023	0	2	2
2024	0	1	1

Below are the most recent publications written about "Adenosine Diphosphate Ribose" by people in Profiles.

Langelier MF, Mirhasan M, Gilbert K, Sverzhinksy A, Furtos A, Pascal JM. PARP enzyme de novo synthesis of protein-free poly(ADP-ribose). Mol Cell. 2024 Dec 19; 84(24):4758-4773.e6.

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Rouleau-Turcotte ?, Pascal JM. ADP-ribose contributions to genome stability and PARP enzyme trapping on sites of DNA damage; paradigm shifts for a coming-of-age modification. J Biol Chem. 2023 12; 299(12):105397.

View in: PubMed
Pascal JM. PARP-nucleic acid interactions: Allosteric signaling, PARP inhibitor types, DNA bridges, and viral RNA surveillance. Curr Opin Struct Biol. 2023 08; 81:102643.

View in: PubMed
Kuttiyatveetil JRA, Soufari H, Dasovich M, Uribe IR, Mirhasan M, Cheng SJ, Leung AKL, Pascal JM. Crystal structures and functional analysis of the ZnF5-WWE1-WWE2 region of PARP13/ZAP define a distinctive mode of engaging poly(ADP-ribose). Cell Rep. 2022 10 25; 41(4):111529.

View in: PubMed
Muoio D, Laspata N, Fouquerel E. Functions of ADP-ribose transferases in the maintenance of telomere integrity. Cell Mol Life Sci. 2022 Mar 29; 79(4):215.

View in: PubMed
Langelier MF, Billur R, Sverzhinsky A, Black BE, Pascal JM. HPF1 dynamically controls the PARP1/2 balance between initiating and elongating ADP-ribose modifications. Nat Commun. 2021 11 18; 12(1):6675.

View in: PubMed
L?scher B, Ahel I, Altmeyer M, Ashworth A, Bai P, Chang P, Cohen M, Corda D, Dantzer F, Daugherty MD, Dawson TM, Dawson VL, Deindl S, Fehr AR, Feijs KLH, Filippov DV, Gagn? JP, Grimaldi G, Guettler S, Hoch NC, Hottiger MO, Korn P, Kraus WL, Ladurner A, Lehti? L, Leung AKL, Lord CJ, Mangerich A, Matic I, Matthews J, Moldovan GL, Moss J, Natoli G, Nielsen ML, Niepel M, Nolte F, Pascal J, Paschal BM, Pawlowski K, Poirier GG, Smith S, Timinszky G, Wang ZQ, Y?lamos J, Yu X, Zaja R, Ziegler M. ADP-ribosyltransferases, an update on function and nomenclature. FEBS J. 2022 12; 289(23):7399-7410.

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Eisemann T, Langelier MF, Pascal JM. Structural and functional analysis of parameters governing tankyrase-1 interaction with telomeric repeat-binding factor 1 and GDP-mannose 4,6-dehydratase. J Biol Chem. 2019 10 04; 294(40):14574-14590.

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Gagn? JP, Langelier MF, Pascal JM, Poirier GG. Hydrofluoric Acid-Based Derivatization Strategy To Profile PARP-1 ADP-Ribosylation by LC-MS/MS. J Proteome Res. 2018 07 06; 17(7):2542-2551.

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Eisemann T, McCauley M, Langelier MF, Gupta K, Roy S, Van Duyne GD, Pascal JM. Tankyrase-1 Ankyrin Repeats Form an Adaptable Binding Platform for Targets of ADP-Ribose Modification. Structure. 2016 Oct 04; 24(10):1679-1692.

View in: PubMed

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