"Sterol O-Acyltransferase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that catalyzes the formation of cholesterol esters by the direct transfer of the fatty acid group from a fatty acyl CoA derivative. This enzyme has been found in the adrenal gland, gonads, liver, intestinal mucosa, and aorta of many mammalian species. EC 2.3.1.26.
| Descriptor ID |
D002785
|
| MeSH Number(s) |
D08.811.913.050.799
|
| Concept/Terms |
Sterol O-Acyltransferase- Sterol O-Acyltransferase
- O-Acyltransferase, Sterol
- Sterol O Acyltransferase
- Cholesterol Esterifying Enzyme
- Enzyme, Cholesterol Esterifying
- Esterifying Enzyme, Cholesterol
- Acyl-CoA-Cholesterol Acyltransferase
- Acyl CoA Cholesterol Acyltransferase
- Acyltransferase, Acyl-CoA-Cholesterol
- Cholesterol Acyltransferase
- Acyltransferase, Cholesterol
|
Below are MeSH descriptors whose meaning is more general than "Sterol O-Acyltransferase".
Below are MeSH descriptors whose meaning is more specific than "Sterol O-Acyltransferase".
This graph shows the total number of publications written about "Sterol O-Acyltransferase" by people in this website by year, and whether "Sterol O-Acyltransferase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 |
| 2002 | 1 | 0 | 1 |
| 2004 | 0 | 1 | 1 |
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Below are the most recent publications written about "Sterol O-Acyltransferase" by people in Profiles.
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Meaney S, Bonfield TL, Hansson M, Babiker A, Kavuru MS, Thomassen MJ. Serum cholestenoic acid as a potential marker of pulmonary cholesterol homeostasis: increased levels in patients with pulmonary alveolar proteinosis. J Lipid Res. 2004 Dec; 45(12):2354-60.
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Rodriguez A, Usher DC. Anti-atherogenic effects of the acyl-CoA:cholesterol acyltransferase inhibitor, avasimibe (CI-1011), in cultured primary human macrophages. Atherosclerosis. 2002 Mar; 161(1):45-54.
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Burgess JW, Frank PG, Franklin V, Liang P, McManus DC, Desforges M, Rassart E, Marcel YL. Deletion of the C-terminal domain of apolipoprotein A-I impairs cell surface binding and lipid efflux in macrophage. Biochemistry. 1999 Nov 2; 38(44):14524-33.