DNA-Binding Proteins

"DNA-Binding Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Proteins which bind to DNA. The family includes proteins which bind to both double- and single-stranded DNA and also includes specific DNA binding proteins in serum which can be used as markers for malignant diseases.

Descriptor ID	D004268
MeSH Number(s)	D12.776.260
Concept/Terms	DNA-Binding Proteins DNA-Binding Proteins DNA Binding Proteins DNA Binding Protein Binding Protein, DNA Single-Stranded DNA Binding Proteins Single-Stranded DNA Binding Proteins Single Stranded DNA Binding Proteins SS DNA BP DNA Single-Stranded Binding Protein DNA Single Stranded Binding Protein Single-Stranded DNA-Binding Protein DNA-Binding Protein, Single-Stranded Single Stranded DNA Binding Protein DNA Helix Destabilizing Proteins DNA Helix Destabilizing Proteins

Below are MeSH descriptors whose meaning is more general than "DNA-Binding Proteins".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
DNA-Binding Proteins [D12.776.260]

Below are MeSH descriptors whose meaning is related to "DNA-Binding Proteins".

Below are MeSH descriptors whose meaning is more specific than "DNA-Binding Proteins".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "DNA-Binding Proteins" by people in this website by year, and whether "DNA-Binding Proteins" was a major or minor topic of these publications.

Bar chart showing 797 publications over 30 distinct years, with a maximum of 75 publications in 2002

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	20	4	24
1997	18	5	23
1998	17	9	26
1999	27	5	32
2000	28	17	45
2001	35	17	52
2002	45	30	75
2003	25	17	42
2004	26	29	55
2005	20	22	42
2006	14	16	30
2007	18	10	28
2008	12	7	19
2009	15	9	24
2010	14	15	29
2011	20	13	33
2012	14	11	25
2013	15	13	28
2014	9	16	25
2015	7	9	16
2016	6	9	15
2017	9	8	17
2018	3	14	17
2019	10	6	16
2020	9	3	12
2021	5	10	15
2022	2	8	10
2023	2	4	6
2024	6	9	15
2025	1	0	1

Below are the most recent publications written about "DNA-Binding Proteins" by people in Profiles.

Wei S, Patchefsky AS, Pei J, Brown SA, Basu Mallick A, Wang Z, Jiang W. PHF1::TFE3-positive fibromyxoid sarcoma? Report of 2 cases and review of 13 cases of PHF1::TFE3-positive ossifying fibromyxoid tumor in the literature. Am J Clin Pathol. 2025 Feb 12; 163(2):224-230.

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Hrizat AS, Lin R, Eberle-Singh J, O'Neill R, Xia Y, Testa JR, Uzzo R, McCue PA, Yang H, Li L. Tumor infiltrating T-cells and loss of expression of SWI/SNF genes in varying stages of clear cell renal cell carcinoma. Pathol Res Pract. 2025 Feb; 266:155774.

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Ben-Crentsil NA, Mohammed Ismail W, Balasis ME, Newman H, Quintana A, Binder M, Kruer T, Neupane S, Ferrall-Fairbanks MC, Fernandez J, Lasho TL, Finke CM, Ibrahim ML, McGraw KL, Wysota M, Aldrich AL, Ryder CB, Letson CT, Traina J, McLemore AF, Droin N, Shastri A, Yun S, Solary E, Sallman DA, Beg AA, Ma L, Gaspar-Maia A, Patnaik MM, Padron E. RNA Shielding of p65 Is Required to Potentiate Oncogenic Inflammation in TET2-Mutated Clonal Hematopoiesis. Cancer Discov. 2024 Dec 02; 14(12):2509-2531.

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Calderon-Aparicio A, He J, Simone NL. S6K1 Controls DNA Damage Signaling Modulated by the MRN Complex to Induce Radioresistance in Lung Cancer. Int J Mol Sci. 2024 Sep 28; 25(19).

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Monda SM, Carney BW, May AM, Gulati S, Salami SS, Chandrasekar T, Keller ET, Huebner NA, Palapattu GS, Dall'Era MA. Differences?in mutations across tumour sizes in clear-cell renal cell carcinoma. BJU Int. 2025 Feb; 135(2):269-278.

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Lee JC, Koo SC, Furtado LV, Breuer A, Eldomery MK, Bag AK, Stow P, Rose G, Larkin T, Sances R, Kleinschmidt-DeMasters BK, Bodmer JL, Willard N, Gokden M, Dahiya S, Roberts K, Bertrand KC, Moreira DC, Robinson GW, Mo JQ, Ellison DW, Orr BA. Concurrent ependymal and ganglionic differentiation in a subset of supratentorial neuroepithelial tumors with EWSR1-PLAGL1 rearrangement. Acta Neuropathol Commun. 2024 09 03; 12(1):143.

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Barnada SM, Giner de Gracia A, Morenilla-Palao C, L?pez-Cascales MT, Scopa C, Waltrich FJ, Mikkers HMM, Cicardi ME, Karlin J, Trotti D, Peterson KA, Brugmann SA, Santen GWE, McMahon SB, Herrera E, Trizzino M. ARID1A-BAF coordinates ZIC2 genomic occupancy for epithelial-to-mesenchymal transition in cranial neural crest specification. Am J Hum Genet. 2024 Oct 03; 111(10):2232-2252.

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Ko YH, Lokareddy RK, Doll SG, Yeggoni DP, Girdhar A, Mawn I, Klim JR, Rizvi NF, Meyers R, Gillilan RE, Guo L, Cingolani G. Single Acetylation-mimetic Mutation in TDP-43 Nuclear Localization Signal Disrupts Importin a1/? Signaling. J Mol Biol. 2024 Oct 15; 436(20):168751.

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Vekariya U, Minakhin L, Chandramouly G, Tyagi M, Kent T, Sullivan-Reed K, Atkins J, Ralph D, Nieborowska-Skorska M, Kukuyan AM, Tang HY, Pomerantz RT, Skorski T. PARG is essential for Pol?-mediated DNA end-joining by removing repressive poly-ADP-ribose marks. Nat Commun. 2024 Jul 11; 15(1):5822.

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Maxwell MB, Hom-Tedla MS, Yi J, Li S, Rivera SA, Yu J, Burns MJ, McRae HM, Stevenson BT, Coakley KE, Ho J, Gastelum KB, Bell JC, Jones AC, Eskander RN, Dykhuizen EC, Shadel GS, Kaech SM, Hargreaves DC. ARID1A suppresses R-loop-mediated STING-type I interferon pathway activation of anti-tumor immunity. Cell. 2024 Jun 20; 187(13):3390-3408.e19.

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