Immunoglobulin alpha-Chains
"Immunoglobulin alpha-Chains" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The class of heavy chains found in IMMUNOGLOBULIN A. They have a molecular weight of approximately 58 kDa and contain about 470 amino acid residues arranged in four domains and an oligosaccharide component bound covalently to their Fc fragment constant region.
| Descriptor ID |
D007137
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| MeSH Number(s) |
D12.776.124.486.485.114.619.026.515 D12.776.124.486.485.705.500.350 D12.776.124.790.651.114.619.026.515 D12.776.124.790.651.705.500.350 D12.776.377.715.548.114.619.026.515 D12.776.377.715.548.705.500.350
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| Concept/Terms |
Immunoglobulin alpha-Chains- Immunoglobulin alpha-Chains
- Immunoglobulin alpha Chains
- alpha-Chains, Immunoglobulin
- Immunoglobulins, alpha-Chain
- Immunoglobulins, alpha Chain
- alpha-Immunoglobulin Heavy Chains
- Heavy Chains, alpha-Immunoglobulin
- alpha Immunoglobulin Heavy Chains
- Immunoglobulin alpha-Chain
- alpha-Chain Immunoglobulins
- alpha Chain Immunoglobulins
- alpha-Immunoglobulin Heavy Chain
- Heavy Chain, alpha-Immunoglobulin
- alpha Immunoglobulin Heavy Chain
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Below are MeSH descriptors whose meaning is more general than "Immunoglobulin alpha-Chains".
Below are MeSH descriptors whose meaning is more specific than "Immunoglobulin alpha-Chains".
This graph shows the total number of publications written about "Immunoglobulin alpha-Chains" by people in this website by year, and whether "Immunoglobulin alpha-Chains" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 1 | 0 | 1 |
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Below are the most recent publications written about "Immunoglobulin alpha-Chains" by people in Profiles.
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Heltemes-Harris L, Liu X, Manser T. An antibody VH gene that promotes marginal zone B cell development and heavy chain allelic inclusion. Int Immunol. 2005 Nov; 17(11):1447-61.
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Kirsch IR, Ravetch JV, Kwan SP, Max EE, Ney RL, Leder P. Multiple immunoglobulin switch region homologies outside the heavy chain constant region locus. Nature. 1981 Oct 15-21; 293(5833):585-7.
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Ravetch JV, Kirsch IR, Leder P. Evolutionary approach to the question of immunoglobulin heavy chain switching: evidence from cloned human and mouse genes. Proc Natl Acad Sci U S A. 1980 Nov; 77(11):6734-8.