"Physostigmine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cholinesterase inhibitor that is rapidly absorbed through membranes. It can be applied topically to the conjunctiva. It also can cross the blood-brain barrier and is used when central nervous system effects are desired, as in the treatment of severe anticholinergic toxicity.
| Descriptor ID |
D010830
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| MeSH Number(s) |
D02.241.081.251.583.682 D03.132.436.545 D03.633.100.473.402.545
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Physostigmine".
Below are MeSH descriptors whose meaning is more specific than "Physostigmine".
This graph shows the total number of publications written about "Physostigmine" by people in this website by year, and whether "Physostigmine" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 1 | 0 | 1 |
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Below are the most recent publications written about "Physostigmine" by people in Profiles.
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Bjornsson TD, Troetel WM, Imbimbo BP. Effect of food on the absorption of eptastigmine. Eur J Clin Pharmacol. 1998 May; 54(3):243-7.
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Dreifus LS, Mazgalev T, Miyagawa A, Michelson EL. Modulation of the effects of postganglionic vagal stimulation in the sinus and atrioventricular nodes by cardioactive agents and electrolytes. Prog Clin Biol Res. 1988; 275:207-23.
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Pelleg A, Mitsuoka T, Mazgalev T, Michelson EL. Vagal component in the chronotropic and dromotropic actions of adenosine and ATP. Prog Clin Biol Res. 1987; 230:375-84.
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Pelleg A, Mitamura H, Mitsuoka T, Michelson EL, Dreifus LS. Effects of adenosine and adenosine 5'-triphosphate on ventricular escape rhythm in the canine heart. J Am Coll Cardiol. 1986 Nov; 8(5):1145-51.
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Pelleg A, Mitamura H, Michelson EL. Evidence for vagal involvement in the electrophysiologic actions of exogenous adenosine and adenosine triphosphate in the canine heart. J Auton Pharmacol. 1985 Sep; 5(3):207-12.
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Saelens JK, Simke JP, Schuman J, Allen MP. Studies with agents which influence acetylcholine metabolism in mouse brain. Arch Int Pharmacodyn Ther. 1974 Jun; 209(2):250-8.