"Suppression, Genetic" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Mutation process that restores the wild-type PHENOTYPE in an organism possessing a mutationally altered GENOTYPE. The second "suppressor" mutation may be on a different gene, on the same gene but located at a distance from the site of the primary mutation, or in extrachromosomal genes (EXTRACHROMOSOMAL INHERITANCE).
| Descriptor ID |
D013489
|
| MeSH Number(s) |
G05.365.590.835 G05.558.835
|
| Concept/Terms |
Suppression, Genetic- Suppression, Genetic
- Genetic Suppression
- Genetic Suppressions
- Suppressions, Genetic
Suppressor Mutation- Suppressor Mutation
- Mutation, Suppressor
- Mutations, Suppressor
- Suppressor Mutations
|
Below are MeSH descriptors whose meaning is more general than "Suppression, Genetic".
Below are MeSH descriptors whose meaning is more specific than "Suppression, Genetic".
This graph shows the total number of publications written about "Suppression, Genetic" by people in this website by year, and whether "Suppression, Genetic" was a major or minor topic of these publications.
To see the data from this visualization as text,
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 2 | 2 |
| 2006 | 1 | 0 | 1 |
| 2008 | 1 | 0 | 1 |
| 2009 | 0 | 1 | 1 |
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Below are the most recent publications written about "Suppression, Genetic" by people in Profiles.
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Natori Y, Tagami K, Murakami K, Yoshida S, Tanigawa O, Moh Y, Masuda K, Wada T, Suzuki S, Nanamiya H, Tozawa Y, Kawamura F. Transcription activity of individual rrn operons in Bacillus subtilis mutants deficient in (p)ppGpp synthetase genes, relA, yjbM, and ywaC. J Bacteriol. 2009 Jul; 191(14):4555-61.
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Park H, Davidson E, King MP. Overexpressed mitochondrial leucyl-tRNA synthetase suppresses the A3243G mutation in the mitochondrial tRNA(Leu(UUR)) gene. RNA. 2008 Nov; 14(11):2407-16.
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Kirino Y, Yasukawa T, Marjavaara SK, Jacobs HT, Holt IJ, Watanabe K, Suzuki T. Acquisition of the wobble modification in mitochondrial tRNALeu(CUN) bearing the G12300A mutation suppresses the MELAS molecular defect. Hum Mol Genet. 2006 Mar 15; 15(6):897-904.
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Matsumura I, Kitamura T, Wakao H, Tanaka H, Hashimoto K, Albanese C, Downward J, Pestell RG, Kanakura Y. Transcriptional regulation of the cyclin D1 promoter by STAT5: its involvement in cytokine-dependent growth of hematopoietic cells. EMBO J. 1999 Mar 01; 18(5):1367-77.
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Mori K, Hatamochi A, Ueki H, Olsen A, Jimenez SA. The transcription of human alpha 1(I) procollagen gene (COL1A1) is suppressed by tumour necrosis factor-alpha through proximal short promoter elements: evidence for suppression mechanisms mediated by two nuclear-factorbinding sites. Biochem J. 1996 Nov 01; 319 ( Pt 3):811-6.
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Smith ST, Jaynes JB. A conserved region of engrailed, shared among all en-, gsc-, Nk1-, Nk2- and msh-class homeoproteins, mediates active transcriptional repression in vivo. Development. 1996 Oct; 122(10):3141-50.
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Bailis AM, Maines S, Negritto MT. The essential helicase gene RAD3 suppresses short-sequence recombination in Saccharomyces cerevisiae. Mol Cell Biol. 1995 Aug; 15(8):3998-4008.
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Prendergast GC, Davide JP, Kral A, Diehl R, Gibbs JB, Omer CA, Kohl NE. Negative growth selection against rodent fibroblasts targeted for genetic inhibition of farnesyl transferase. Cell Growth Differ. 1993 Sep; 4(9):707-13.
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Mizrokhi LIu, Mazo AM, Karavanov AA, Sedkov IuA, Krichevskaia AA. [Interaction of products of su(Hw) and su(f) genes with MDG4 region regulating its transcription suppresses mutations in Drosophila caused by insertion of this gene]. Genetika. 1989 May; 25(5):784-98.
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Mazo AM, Mizrokhi LJ, Karavanov AA, Sedkov YA, Krichevskaja AA, Ilyin YV. Suppression in Drosophila: su(Hw) and su(f) gene products interact with a region of gypsy (mdg4) regulating its transcriptional activity. EMBO J. 1989 Mar; 8(3):903-11.