"Genes, src" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Retrovirus-associated DNA sequences (src) originally isolated from the Rous sarcoma virus (RSV). The proto-oncogene src (c-src) codes for a protein that is a member of the tyrosine kinase family and was the first proto-oncogene identified in the human genome. The human c-src gene is located at 20q12-13 on the long arm of chromosome 20.
| Descriptor ID |
D016391
|
| MeSH Number(s) |
G05.360.340.024.340.375.500.791.570
|
| Concept/Terms |
src Oncogene- src Oncogene
- Oncogene, src
- Oncogenes, src
- src Oncogenes
- v-src Oncogenes
- Oncogene, v-src
- Oncogenes, v-src
- v src Oncogenes
- v-src Oncogene
- v-src Genes
- Gene, v-src
- Genes, v-src
- v src Genes
- v-src Gene
c-src Genes- c-src Genes
- Gene, c-src
- Genes, c-src
- c src Genes
- c-src Gene
- c-src Proto-Oncogenes
- Proto-Oncogene, c-src
- Proto-Oncogenes, c-src
- c src Proto Oncogenes
- c-src Proto-Oncogene
|
Below are MeSH descriptors whose meaning is more general than "Genes, src".
Below are MeSH descriptors whose meaning is more specific than "Genes, src".
This graph shows the total number of publications written about "Genes, src" by people in this website by year, and whether "Genes, src" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 1 | 0 | 1 |
| 2005 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2008 | 1 | 0 | 1 |
| 2012 | 0 | 1 | 1 |
| 2013 | 1 | 0 | 1 |
| 2014 | 1 | 0 | 1 |
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click here.
Below are the most recent publications written about "Genes, src" by people in Profiles.
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Sicoli D, Jiao X, Ju X, Velasco-Velazquez M, Ertel A, Addya S, Li Z, And? S, Fatatis A, Paudyal B, Cristofanilli M, Thakur ML, Lisanti MP, Pestell RG. CCR5 receptor antagonists block metastasis to bone of v-Src oncogene-transformed metastatic prostate cancer cell lines. Cancer Res. 2014 Dec 01; 74(23):7103-14.
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Deangelis T, Quong A, Morrione A, Baserga R. Growth of v-src-transformed cells in serum-free medium through the induction of growth factors. J Cell Physiol. 2013 Jul; 228(7):1482-6.
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Ju X, Ertel A, Casimiro MC, Yu Z, Meng H, McCue PA, Walters R, Fortina P, Lisanti MP, Pestell RG. Novel oncogene-induced metastatic prostate cancer cell lines define human prostate cancer progression signatures. Cancer Res. 2013 Jan 15; 73(2):978-89.
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Jiao X, Katiyar S, Liu M, Mueller SC, Lisanti MP, Li A, Pestell TG, Wu K, Ju X, Li Z, Wagner EF, Takeya T, Wang C, Pestell RG. Disruption of c-Jun reduces cellular migration and invasion through inhibition of c-Src and hyperactivation of ROCK II kinase. Mol Biol Cell. 2008 Apr; 19(4):1378-90.
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Scotlandi K, Zuntini M, Manara MC, Sciandra M, Rocchi A, Benini S, Nicoletti G, Bernard G, Nanni P, Lollini PL, Bernard A, Picci P. CD99 isoforms dictate opposite functions in tumour malignancy and metastases by activating or repressing c-Src kinase activity. Oncogene. 2007 Oct 11; 26(46):6604-18.
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Morgan JC, Majors JE, Galileo DS. Distinct and opposite roles for SH2 and SH3 domains of v-src in embryo survival and hemangiosarcoma formation. Clin Exp Metastasis. 2005; 22(2):167-75.
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Valentinis B, Morrione A, Taylor SJ, Baserga R. Insulin-like growth factor I receptor signaling in transformation by src oncogenes. Mol Cell Biol. 1997 Jul; 17(7):3744-54.