"Genes, myb" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Retrovirus-associated DNA sequences (v-myb) originally isolated from the avian myeloblastosis and E26 leukemia viruses. The proto-oncogene c-myb codes for a nuclear protein involved in transcriptional regulation and appears to be essential for hematopoietic cell proliferation. The human myb gene is located at 6q22-23 on the short arm of chromosome 6. This is the point of break in translocations involved in T-cell acute lymphatic leukemia and in some ovarian cancers and melanomas. (From Ibelgaufts, Dictionary of Cytokines, 1995).
| Descriptor ID |
D020570
|
| MeSH Number(s) |
G05.360.340.024.340.375.500.791.418
|
| Concept/Terms |
v-myb Genes- v-myb Genes
- Gene, v-myb
- Genes, v-myb
- v myb Genes
- v-myb Gene
- myb Oncogene
- Oncogene, myb
- Oncogenes, myb
- myb Oncogenes
- v-myb Oncogenes
- Oncogene, v-myb
- Oncogenes, v-myb
- v myb Oncogenes
- v-myb Oncogene
c-myb Genes- c-myb Genes
- Gene, c-myb
- Genes, c-myb
- c myb Genes
- c-myb Gene
- c-myb Proto-Oncogenes
- Proto-Oncogene, c-myb
- Proto-Oncogenes, c-myb
- c myb Proto Oncogenes
- c-myb Proto-Oncogene
|
Below are MeSH descriptors whose meaning is more general than "Genes, myb".
Below are MeSH descriptors whose meaning is more specific than "Genes, myb".
This graph shows the total number of publications written about "Genes, myb" by people in this website by year, and whether "Genes, myb" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 1 | 0 | 1 |
| 2002 | 1 | 0 | 1 |
| 2007 | 1 | 0 | 1 |
| 2008 | 1 | 0 | 1 |
| 2011 | 0 | 1 | 1 |
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Below are the most recent publications written about "Genes, myb" by people in Profiles.
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Cesi V, Casciati A, Sesti F, Tanno B, Calabretta B, Raschell? G. TGF?-induced c-Myb affects the expression of EMT-associated genes and promotes invasion of ER+ breast cancer cells. Cell Cycle. 2011 Dec 01; 10(23):4149-61.
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Soliera AR, Lidonnici MR, Ferrari-Amorotti G, Prisco M, Zhang Y, Martinez RV, Donato NJ, Calabretta B. Transcriptional repression of c-Myb and GATA-2 is involved in the biologic effects of C/EBPalpha in p210BCR/ABL-expressing cells. Blood. 2008 Sep 01; 112(5):1942-50.
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Schwab R, Bussolari R, Corvetta D, Chayka O, Santilli G, Kwok JM, Ferrari-Amorotti G, Amorotti GF, Tonini GP, Iacoviello L, Bertorelle R, Menin C, Hubank M, Calabretta B, Sala A. Isolation and functional assessment of common, polymorphic variants of the B-MYB proto-oncogene associated with a reduced cancer risk. Oncogene. 2008 May 01; 27(20):2929-33.
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Tanno B, Negroni A, Vitali R, Pirozzoli MC, Cesi V, Mancini C, Calabretta B, Raschell? G. Expression of insulin-like growth factor-binding protein 5 in neuroblastoma cells is regulated at the transcriptional level by c-Myb and B-Myb via direct and indirect mechanisms. J Biol Chem. 2002 Jun 28; 277(26):23172-80.
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Manzella L, Gualdi R, Perrotti D, Nicolaides NC, Girlando G, Giuffrida MA, Messina A, Calabretta B. The interferon regulatory factors 1 and 2 bind to a segment of the human c-myb first intron: possible role in the regulation of c-myb expression. Exp Cell Res. 2000 Apr 10; 256(1):248-56.