"Fibrinopeptide A" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Two small peptide chains removed from the N-terminal segment of the alpha chains of fibrinogen by the action of thrombin during the blood coagulation process. Each peptide chain contains 18 amino acid residues. In vivo, fibrinopeptide A is used as a marker to determine the rate of conversion of fibrinogen to fibrin by thrombin.
| Descriptor ID |
D005344
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| MeSH Number(s) |
D12.644.200 D12.776.124.125.515 D12.776.124.270.310 D12.776.811.300.310 D23.101.340 D23.119.500
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Fibrinopeptide A".
Below are MeSH descriptors whose meaning is more specific than "Fibrinopeptide A".
This graph shows the total number of publications written about "Fibrinopeptide A" by people in this website by year, and whether "Fibrinopeptide A" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 2000 | 0 | 1 | 1 |
| 2002 | 0 | 2 | 2 |
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Below are the most recent publications written about "Fibrinopeptide A" by people in Profiles.
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Akhavan S, De Cristofaro R, Peyvandi F, Lavoretano S, Landolfi R, Mannucci PM. Molecular and functional characterization of a natural homozygous Arg67His mutation in the prothrombin gene of a patient with a severe procoagulant defect contrasting with a mild hemorrhagic phenotype. Blood. 2002 Aug 15; 100(4):1347-53.
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De CR, Rocca B, Marchioli R, Landolfi R. Plasma protein oxidation is associated with an increase of procoagulant markers causing an imbalance between pro- and anticoagulant pathways in healthy subjects. Thromb Haemost. 2002 Jan; 87(1):58-67.
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De Cristofaro R, Landolfi R. Oxidation of human alpha-thrombin by the myeloperoxidase-H2O2-chloride system: structural and functional effects. Thromb Haemost. 2000 Feb; 83(2):253-61.
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Ragni M, Cirillo P, Pascucci I, Scognamiglio A, D'Andrea D, Eramo N, Ezekowitz MD, Pawashe AB, Chiariello M, Golino P. Monoclonal antibody against tissue factor shortens tissue plasminogen activator lysis time and prevents reocclusion in a rabbit model of carotid artery thrombosis. Circulation. 1996 May 15; 93(10):1913-8.