"Haptens" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Small antigenic determinants capable of eliciting an immune response only when coupled to a carrier. Haptens bind to antibodies but by themselves cannot elicit an antibody response.
Descriptor ID |
D006241
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MeSH Number(s) |
D23.050.550.480
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Haptens".
Below are MeSH descriptors whose meaning is more specific than "Haptens".
This graph shows the total number of publications written about "Haptens" by people in this website by year, and whether "Haptens" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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1995 | 0 | 1 | 1 |
1997 | 0 | 4 | 4 |
1998 | 1 | 1 | 2 |
1999 | 1 | 1 | 2 |
2000 | 1 | 1 | 2 |
2001 | 1 | 1 | 2 |
2002 | 0 | 2 | 2 |
2003 | 1 | 0 | 1 |
2007 | 0 | 1 | 1 |
2008 | 0 | 2 | 2 |
2011 | 0 | 1 | 1 |
2016 | 1 | 0 | 1 |
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click here.
Below are the most recent publications written about "Haptens" by people in Profiles.
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Mhike M, Hettick JM, Chipinda I, Law BF, Bledsoe TA, Lemons AR, Nayak AP, Green BJ, Beezhold DH, Simoyi RH, Siegel PD. Characterization and comparative analysis of 2,4-toluene diisocyanate and 1,6-hexamethylene diisocyanate haptenated human serum albumin and hemoglobin. J Immunol Methods. 2016 Apr; 431:38-44.
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Mahipal A, Terai M, Berd D, Chervoneva I, Patel K, Mastrangelo MJ, Sato T. Tumor-derived interleukin-10 as a prognostic factor in stage III patients undergoing adjuvant treatment with an autologous melanoma cell vaccine. Cancer Immunol Immunother. 2011 Jul; 60(7):1039-45.
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Alabyev B, Vuyyuru R, Manser T. Influence of Fas on the regulation of the response of an anti-nuclear antigen B cell clonotype to foreign antigen. Int Immunol. 2008 Oct; 20(10):1279-87.
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Gober MD, Gaspari AA. Allergic contact dermatitis. Curr Dir Autoimmun. 2008; 10:1-26.
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Coffey F, Liu X, Manser T. Primary development and participation in a foreign antigen-driven immune response of a chromatin-reactive B cell clonotype are not influenced by TLR9 or other MyD88-dependent TLRs. J Immunol. 2007 Nov 15; 179(10):6663-72.
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Berd D, Sato T, Maguire HC, Kairys J, Mastrangelo MJ. Immunopharmacologic analysis of an autologous, hapten-modified human melanoma vaccine. J Clin Oncol. 2004 Feb 1; 22(3):403-15.
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Notidis E, Heltemes L, Manser T. Dominant, hierarchical induction of peripheral tolerance during foreign antigen-driven B cell development. Immunity. 2002 Sep; 17(3):317-27.
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Berd D, Sato T, Mastrangelo MJ. Effect of the dose and composition of an autologous hapten-modified melanoma vaccine on the development of delayed-type hypersensitivity responses. Cancer Immunol Immunother. 2002 Aug; 51(6):320-6.
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Berd D, Sato T, Cohn H, Maguire HC, Mastrangelo MJ. Treatment of metastatic melanoma with autologous, hapten-modified melanoma vaccine: regression of pulmonary metastases. Int J Cancer. 2001 Nov; 94(4):531-9.
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Dasgupta A, Kesari KV, Ramaswamy KK, Amenta PS, Das KM. Oral administration of unmodified colonic but not small intestinal antigens protects rats from hapten-induced colitis. Clin Exp Immunol. 2001 Jul; 125(1):41-7.