"Immunoglobulin mu-Chains" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The class of heavy chains found in IMMUNOGLOBULIN M. They have a molecular weight of approximately 72 kDa and they contain about 57 amino acid residues arranged in five domains and have more oligosaccharide branches and a higher carbohydrate content than the heavy chains of IMMUNOGLOBULIN G.
| Descriptor ID |
D007148
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| MeSH Number(s) |
D12.776.124.486.485.114.619.574.500 D12.776.124.486.485.705.500.500 D12.776.124.790.651.114.619.574.500 D12.776.124.790.651.705.500.500 D12.776.377.715.548.114.619.574.500 D12.776.377.715.548.705.500.500
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| Concept/Terms |
Immunoglobulin mu-Chains- Immunoglobulin mu-Chains
- Immunoglobulin mu Chains
- mu-Chains, Immunoglobulin
- mu-Chain Immunoglobulins
- mu Chain Immunoglobulins
- mu Immunoglobulin Heavy Chain
- mu Immunoglobulin Heavy Chains
- Immunoglobulin mu-Chain
- Immunoglobulin mu Chain
- mu-Chain, Immunoglobulin
- Immunoglobulins, mu-Chain
- Immunoglobulins, mu Chain
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Below are MeSH descriptors whose meaning is more general than "Immunoglobulin mu-Chains".
Below are MeSH descriptors whose meaning is more specific than "Immunoglobulin mu-Chains".
This graph shows the total number of publications written about "Immunoglobulin mu-Chains" by people in this website by year, and whether "Immunoglobulin mu-Chains" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 1998 | 0 | 1 | 1 |
| 1999 | 2 | 1 | 3 |
| 2009 | 0 | 1 | 1 |
| 2012 | 1 | 0 | 1 |
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Below are the most recent publications written about "Immunoglobulin mu-Chains" by people in Profiles.
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Hardy RR, Hayakawa K. Positive and negative selection of natural autoreactive B cells. Adv Exp Med Biol. 2012; 750:227-38.
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Nakajima PB, Kiefer K, Price A, Bosma GC, Bosma MJ. Two distinct populations of H chain-edited B cells show differential surrogate L chain dependence. J Immunol. 2009 Mar 15; 182(6):3583-96.
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Bosma GC, Chang Y, Karasuyama H, Bosma MJ. Differential effect of an Ig mu transgene on development of pre-B cells in fetal and adult SCID mice. Proc Natl Acad Sci U S A. 1999 Oct 12; 96(21):11952-7.
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Wang Z, Goldstein A, Zong RT, Lin D, Neufeld EJ, Scheuermann RH, Tucker PW. Cux/CDP homeoprotein is a component of NF-muNR and represses the immunoglobulin heavy chain intronic enhancer by antagonizing the bright transcription activator. Mol Cell Biol. 1999 Jan; 19(1):284-95.
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Webb C, Zong RT, Lin D, Wang Z, Kaplan M, Paulin Y, Smith E, Probst L, Bryant J, Goldstein A, Scheuermann R, Tucker P. Differential regulation of immunoglobulin gene transcription via nuclear matrix-associated regions. Cold Spring Harb Symp Quant Biol. 1999; 64:109-18.
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Wasserman R, Li YS, Shinton SA, Carmack CE, Manser T, Wiest DL, Hayakawa K, Hardy RR. A novel mechanism for B cell repertoire maturation based on response by B cell precursors to pre-B receptor assembly. J Exp Med. 1998 Jan 19; 187(2):259-64.
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Racila E, Hsueh R, Marches R, Tucker TF, Krammer PH, Scheuermann RH, Uhr JW. Tumor dormancy and cell signaling: anti-mu-induced apoptosis in human B-lymphoma cells is not caused by an APO-1-APO-1 ligand interaction. Proc Natl Acad Sci U S A. 1996 Mar 05; 93(5):2165-8.
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Kotloff DB, Bosma MJ, Ruetsch NR. Scid mouse Pre-B cells with intracellular mu chains: analysis of recombinase activity and IgH gene rearrangements. Int Immunol. 1993 Apr; 5(4):383-91.
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Reichman-Fried M, Bosma MJ, Hardy RR. B-lineage cells in mu-transgenic scid mice proliferate in response to IL-7 but fail to show evidence of immunoglobulin light chain gene rearrangement. Int Immunol. 1993 Mar; 5(3):303-10.
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Schwaber J, Malone B. Germ line transcription of the immunoglobulin heavy chain locus directs production of mu chain without VDJ. J Clin Invest. 1992 Jun; 89(6):2046-52.