"Pro-Opiomelanocortin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 30-kDa protein synthesized primarily in the ANTERIOR PITUITARY GLAND and the HYPOTHALAMUS. It is also found in the skin and other peripheral tissues. Depending on species and tissues, POMC is cleaved by PROHORMONE CONVERTASES yielding various active peptides including ACTH; BETA-LIPOTROPIN; ENDORPHINS; MELANOCYTE-STIMULATING HORMONES; and others (GAMMA-LPH; CORTICOTROPIN-LIKE INTERMEDIATE LOBE PEPTIDE; N-terminal peptide of POMC or NPP).
| Descriptor ID |
D011333
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| MeSH Number(s) |
D06.472.699.327.935 D06.472.699.631.525.600 D12.644.400.400.935 D12.644.548.365.935 D12.644.548.691.525.690 D12.776.631.650.405.935 D12.776.811.800
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| Concept/Terms |
Pro-Opiomelanocortin- Pro-Opiomelanocortin
- Pro Opiomelanocortin
- ACTH-Endorphin Precursor
- ACTH Endorphin Precursor
- Endorphin-ACTH Precursor
- Endorphin ACTH Precursor
- Corticotropin-beta-Lipotropin Precursor
- Corticotropin beta Lipotropin Precursor
- POMC
- Proopiomelanocortin
- Pro-Opiocortin
- Pro Opiocortin
- Pro-Opio-Melanocortin
- Pro Opio Melanocortin
- Proopiocortin
- ACTH-beta-Lipotropin Precursor
- ACTH beta Lipotropin Precursor
- Pro-ACTH-Endorphin
- Pro ACTH Endorphin
|
Below are MeSH descriptors whose meaning is more general than "Pro-Opiomelanocortin".
Below are MeSH descriptors whose meaning is more specific than "Pro-Opiomelanocortin".
This graph shows the total number of publications written about "Pro-Opiomelanocortin" by people in this website by year, and whether "Pro-Opiomelanocortin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 1 | 0 | 1 |
| 2006 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
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Below are the most recent publications written about "Pro-Opiomelanocortin" by people in Profiles.
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Shenoda BB, Alexander GM, Ajit SK. Hsa-miR-34a mediated repression of corticotrophin releasing hormone receptor 1 regulates pro-opiomelanocortin expression in patients with complex regional pain syndrome. J Transl Med. 2016 Mar 03; 14:64.
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Reyes BA, Glaser JD, Magtoto R, Van Bockstaele EJ. Pro-opiomelanocortin colocalizes with corticotropin- releasing factor in axon terminals of the noradrenergic nucleus locus coeruleus. Eur J Neurosci. 2006 Apr; 23(8):2067-77.
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Coulter CL, Pestell RG, Ross JT, Salkeld MD, James S, Bennett HP, McMillen IC. Effect of N-proopiomelanocortin (1-77) and (1-49) infusions on adrenal expression of cyclin D1 in the fetal sheep. Endocr Res. 2002 Nov; 28(4):625-9.