Tumor Suppressor p53-Binding Protein 1
"Tumor Suppressor p53-Binding Protein 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
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A nuclear and cytoplasmic protein that associates with KINETOCHORES and contains a C-terminal TUDOR DOMAIN. It plays a critical role in the cellular response to DNA DAMAGE and localizes to DOUBLE-STRAND DNA BREAKS. It may also function in M PHASE CELL CYCLE CHECKPOINTS and as an enhancer of TUMOR SUPPRESSOR PROTEIN P53-mediated transcriptional activation.
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