Tumor Suppressor p53-Binding Protein 1
"Tumor Suppressor p53-Binding Protein 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A nuclear and cytoplasmic protein that associates with KINETOCHORES and contains a C-terminal TUDOR DOMAIN. It plays a critical role in the cellular response to DNA DAMAGE and localizes to DOUBLE-STRAND DNA BREAKS. It may also function in M PHASE CELL CYCLE CHECKPOINTS and as an enhancer of TUMOR SUPPRESSOR PROTEIN P53-mediated transcriptional activation.
Descriptor ID |
D000071857
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MeSH Number(s) |
D12.776.260.805 D12.776.660.235.850 D12.776.664.235.950
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Concept/Terms |
Tumor Suppressor p53-Binding Protein 1- Tumor Suppressor p53-Binding Protein 1
- Tumor Suppressor p53 Binding Protein 1
- TP53BP1 Protein
- p202 Protein
- Tumor Protein p53-Binding Protein, 1
- Tumor Protein p53 Binding Protein, 1
- 53BP1 Protein
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Below are MeSH descriptors whose meaning is more general than "Tumor Suppressor p53-Binding Protein 1".
Below are MeSH descriptors whose meaning is more specific than "Tumor Suppressor p53-Binding Protein 1".
This graph shows the total number of publications written about "Tumor Suppressor p53-Binding Protein 1" by people in this website by year, and whether "Tumor Suppressor p53-Binding Protein 1" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2003 | 0 | 1 | 1 |
2011 | 0 | 1 | 1 |
2015 | 0 | 1 | 1 |
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Below are the most recent publications written about "Tumor Suppressor p53-Binding Protein 1" by people in Profiles.
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Torres MJ, Pandita RK, Kulak O, Kumar R, Formstecher E, Horikoshi N, Mujoo K, Hunt CR, Zhao Y, Lum L, Zaman A, Yeaman C, White MA, Pandita TK. Role of the Exocyst Complex Component Sec6/8 in Genomic Stability. Mol Cell Biol. 2015 Nov; 35(21):3633-45.
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Chiba N, Comaills V, Shiotani B, Takahashi F, Shimada T, Tajima K, Winokur D, Hayashida T, Willers H, Brachtel E, Vivanco MD, Haber DA, Zou L, Maheswaran S. Homeobox B9 induces epithelial-to-mesenchymal transition-associated radioresistance by accelerating DNA damage responses. Proc Natl Acad Sci U S A. 2012 Feb 21; 109(8):2760-5.
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Wen Y, Giri D, Yan DH, Spohn B, Zinner RG, Xia W, Thompson TC, Matusik RJ, Hung MC. Prostate-specific antitumor activity by probasin promoter-directed p202 expression. Mol Carcinog. 2003 Jul; 37(3):130-7.