"MRE11 Homologue Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
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A component of the MRN complex along with Rad50 and Nibrin. Together, these perform a critical function in the repair of DOUBLE-STRANDED DNA BREAKS; RECOMBINATIONAL DNA REPAIR; maintenance of TELOMERE integrity and MEIOSIS. MRE11, which contains a poly(ADP)-ribose binding motif and associates with PARP1, possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Mutations in the MRE11 gene are associated with ATAXIA-TELANGIECTASIA-like disorder 1.
|MRE11 Homologue Protein
- MRE11 Homologue Protein
- Homologue Protein, MRE11
- MRE11A Protein
- Meiotic Recombination 11 Homolog 1 Protein
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