Below are the most recent publications written about "Mutagenesis" by people in Profiles.
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Bohm KA, Morledge-Hampton B, Stevison S, Mao P, Roberts SA, Wyrick JJ. Genome-wide maps of rare and atypical UV photoproducts reveal distinct patterns of damage formation and mutagenesis in yeast chromatin. Proc Natl Acad Sci U S A. 2023 Mar 07; 120(10):e2216907120.
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Mertz TM, Collins CD, Dennis M, Coxon M, Roberts SA. APOBEC-Induced Mutagenesis in Cancer. Annu Rev Genet. 2022 11 30; 56:229-252.
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Antony JS, Roberts SA, Wyrick JJ, Hinz JM. dCas9 binding inhibits the initiation of base excision repair in vitro. DNA Repair (Amst). 2022 01; 109:103257.
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Bonilla B, Brown AJ, Hengel SR, Rapchak KS, Mitchell D, Pressimone CA, Fagunloye AA, Luong TT, Russell RA, Vyas RK, Mertz TM, Zaher HS, Mosammaparast N, Malc EP, Mieczkowski PA, Roberts SA, Bernstein KA. The Shu complex prevents mutagenesis and cytotoxicity of single-strand specific alkylation lesions. Elife. 2021 11 01; 10.
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Vile RG, Melcher A, Pandha H, Harrington KJ, Pulido JS. APOBEC and Cancer Viroimmunotherapy: Thinking the Unthinkable. Clin Cancer Res. 2021 06 15; 27(12):3280-3290.
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Cingolani G, McCauley M, Lobley A, Bryer AJ, Wesolowski J, Greco DL, Lokareddy RK, Ronzone E, Perilla JR, Paumet F. Structural basis for the homotypic fusion of chlamydial inclusions by the SNARE-like protein IncA. Nat Commun. 2019 06 21; 10(1):2747.
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Jiang J, Hu Z, Lyons KM. Design and Analysis of CCN Gene Activity Using CCN Knockout Mice Containing LacZ Reporters. Methods Mol Biol. 2017; 1489:325-345.
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Saini N, Roberts SA, Klimczak LJ, Chan K, Grimm SA, Dai S, Fargo DC, Boyer JC, Kaufmann WK, Taylor JA, Lee E, Cortes-Ciriano I, Park PJ, Schurman SH, Malc EP, Mieczkowski PA, Gordenin DA. The Impact of Environmental and Endogenous Damage on Somatic Mutation Load in Human Skin Fibroblasts. PLoS Genet. 2016 10; 12(10):e1006385.
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Wyrick JJ, Roberts SA. Genomic approaches to DNA repair and mutagenesis. DNA Repair (Amst). 2015 Dec; 36:146-55.
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Chan K, Roberts SA, Klimczak LJ, Sterling JF, Saini N, Malc EP, Kim J, Kwiatkowski DJ, Fargo DC, Mieczkowski PA, Getz G, Gordenin DA. An APOBEC3A hypermutation signature is distinguishable from the signature of background mutagenesis by APOBEC3B in human cancers. Nat Genet. 2015 Sep; 47(9):1067-72.