Proto-Oncogene Proteins pp60(c-src)
"Proto-Oncogene Proteins pp60(c-src)" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Membrane-associated tyrosine-specific kinases encoded by the c-src genes. They have an important role in cellular growth control. Truncation of carboxy-terminal residues in pp60(c-src) leads to PP60(V-SRC) which has the ability to transform cells. This kinase pp60 c-src should not be confused with csk, also known as c-src kinase.
Descriptor ID |
D016392
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MeSH Number(s) |
D08.811.913.696.620.682.725.800.630 D12.776.624.664.700.202
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Concept/Terms |
Proto-Oncogene Proteins pp60(c-src)- Proto-Oncogene Proteins pp60(c-src)
- Phosphoprotein pp60(c-src)
- pp60 c-src
- c-src, pp60
- pp60 c src
- pp60(c-src)
- Proto-Oncogene Protein src
- Protein src, Proto-Oncogene
- Proto Oncogene Protein src
- src Proto-Oncogene Product
- Proto-Oncogene Product, src
- src Proto Oncogene Product
- src Proto-Oncogene Protein pp60
- src Proto Oncogene Protein pp60
- c-src Protein pp60
- Protein pp60, c-src
- c src Protein pp60
- pp60, c-src Protein
- Proto-Oncogene Protein pp60(c-src)
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Below are MeSH descriptors whose meaning is more general than "Proto-Oncogene Proteins pp60(c-src)".
Below are MeSH descriptors whose meaning is more specific than "Proto-Oncogene Proteins pp60(c-src)".
This graph shows the total number of publications written about "Proto-Oncogene Proteins pp60(c-src)" by people in this website by year, and whether "Proto-Oncogene Proteins pp60(c-src)" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2002 | 1 | 0 | 1 |
2008 | 1 | 0 | 1 |
2009 | 1 | 1 | 2 |
2011 | 0 | 2 | 2 |
2012 | 0 | 1 | 1 |
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Below are the most recent publications written about "Proto-Oncogene Proteins pp60(c-src)" by people in Profiles.
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Dong X, Tang W, Stopenski S, Brose MS, Korch C, Meinkoth JL. RAP1GAP inhibits cytoskeletal remodeling and motility in thyroid cancer cells. Endocr Relat Cancer. 2012 Aug; 19(4):575-88.
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Saxena P, Trerotola M, Wang T, Li J, Sayeed A, Vanoudenhove J, Adams DS, Fitzgerald TJ, Altieri DC, Languino LR. PSA regulates androgen receptor expression in prostate cancer cells. Prostate. 2012 May 15; 72(7):769-76.
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Argiris A, Feinstein TM, Wang L, Yang T, Agrawal S, Appleman LJ, Stoller RG, Grandis JR, Egloff AM. Phase I and pharmacokinetic study of dasatinib and cetuximab in patients with advanced solid malignancies. Invest New Drugs. 2012 Aug; 30(4):1575-84.
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Schuh NR, Guerrero MS, Schrecengost RS, Bouton AH. BCAR3 regulates Src/p130 Cas association, Src kinase activity, and breast cancer adhesion signaling. J Biol Chem. 2010 Jan 22; 285(4):2309-17.
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Selvakumar P, Lakshmikuttyamma A, Das U, Pati HN, Dimmock JR, Sharma RK. NC2213: a novel methionine aminopeptidase 2 inhibitor in human colon cancer HT29 cells. Mol Cancer. 2009; 8:65.
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Inge LJ, Rajasekaran SA, Wolle D, Barwe SP, Ryazantsev S, Ewing CM, Isaacs WB, Rajasekaran AK. alpha-Catenin overrides Src-dependent activation of beta-catenin oncogenic signaling. Mol Cancer Ther. 2008 Jun; 7(6):1386-97.
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Puri RN, Fan YP, Rattan S. Role of pp60(c-src) and p(44/42) MAPK in ANG II-induced contraction of rat tonic gastrointestinal smooth muscles. Am J Physiol Gastrointest Liver Physiol. 2002 Aug; 283(2):G390-9.