Prostate-Specific Antigen

"Prostate-Specific Antigen" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A glycoprotein that is a kallikrein-like serine proteinase and an esterase, produced by epithelial cells of both normal and malignant prostate tissue. It is an important marker for the diagnosis of prostate cancer.

Descriptor ID	D017430
MeSH Number(s)	D08.811.277.656.300.760.442.750 D08.811.277.656.959.350.442.750 D12.776.866.249.500 D23.050.285.625 D23.101.140.625
Concept/Terms	Prostate-Specific Antigen Prostate-Specific Antigen gamma-Seminoprotein gamma Seminoprotein Prostate Specific Antigen hK3 Kallikrein Kallikrein, hK3 Semenogelase Kallikrein hK3 Seminin

Below are MeSH descriptors whose meaning is more general than "Prostate-Specific Antigen".

Chemicals and Drugs [D]
Enzymes and Coenzymes [D08]
Enzymes [D08.811]
Hydrolases [D08.811.277]
Peptide Hydrolases [D08.811.277.656]
Endopeptidases [D08.811.277.656.300]
Serine Endopeptidases [D08.811.277.656.300.760]
Kallikreins [D08.811.277.656.300.760.442]
Prostate-Specific Antigen [D08.811.277.656.300.760.442.750]
Serine Proteases [D08.811.277.656.959]
Serine Endopeptidases [D08.811.277.656.959.350]
Kallikreins [D08.811.277.656.959.350.442]
Prostate-Specific Antigen [D08.811.277.656.959.350.442.750]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Seminal Plasma Proteins [D12.776.866]
Prostatic Secretory Proteins [D12.776.866.249]
Prostate-Specific Antigen [D12.776.866.249.500]
Biological Factors [D23]
Antigens [D23.050]
Antigens, Neoplasm [D23.050.285]
Prostate-Specific Antigen [D23.050.285.625]
Biomarkers [D23.101]
Biomarkers, Tumor [D23.101.140]
Prostate-Specific Antigen [D23.101.140.625]

Below are MeSH descriptors whose meaning is related to "Prostate-Specific Antigen".

Below are MeSH descriptors whose meaning is more specific than "Prostate-Specific Antigen".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Prostate-Specific Antigen" by people in this website by year, and whether "Prostate-Specific Antigen" was a major or minor topic of these publications.

Bar chart showing 318 publications over 30 distinct years, with a maximum of 19 publications in 2007 and 2009

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1995	1	3	4
1996	7	4	11
1997	5	4	9
1998	7	7	14
1999	2	5	7
2000	5	12	17
2001	5	2	7
2002	8	6	14
2003	5	13	18
2004	3	10	13
2005	4	10	14
2006	1	6	7
2007	5	14	19
2008	3	12	15
2009	4	15	19
2010	6	9	15
2011	6	10	16
2012	2	4	6
2013	4	2	6
2014	5	9	14
2015	0	1	1
2016	0	3	3
2017	4	4	8
2018	4	1	5
2019	2	6	8
2020	4	10	14
2021	1	5	6
2022	3	6	9
2023	3	8	11
2024	3	5	8

Below are the most recent publications written about "Prostate-Specific Antigen" by people in Profiles.

Marshall CH, Teply BA, Lu J, Oliveira L, Wang H, Mao SS, Kelly WK, Paller CJ, Markowski MC, Denmeade SR, King S, Sullivan R, Davicioni E, Proudfoot JA, Eisenberger MA, Carducci MA, Lotan TL, Antonarakis ES. Olaparib Without Androgen Deprivation for High-Risk Biochemically Recurrent Prostate Cancer Following Prostatectomy: A Nonrandomized Controlled Trial. JAMA Oncol. 2024 Oct 01; 10(10):1400-1408.

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Morris MJ, Castellano D, Herrmann K, de Bono JS, Shore ND, Chi KN, Crosby M, Piulats JM, Fl?chon A, Wei XX, Mahammedi H, Roubaud G, ?tudentov? H, Nagarajah J, Mellado B, Montesa-Pino ?, Kpamegan E, Ghebremariam S, Kreisl TN, Wilke C, Lehnhoff K, Sartor O, Fizazi K. 177Lu-PSMA-617 versus a change of androgen receptor pathway inhibitor therapy for taxane-naive patients with progressive metastatic castration-resistant prostate cancer (PSMAfore): a phase 3, randomised, controlled trial. Lancet. 2024 Sep 28; 404(10459):1227-1239.

View in: PubMed
Shore N, Hafron J, Saltzstein D, Brown G, Belkoff L, Aggarwal P, Phillips J, Bhaumik A, McGowan T. Apalutamide for High-Risk Localized Prostate Cancer Following Radical Prostatectomy (Apa-RP). J Urol. 2024 Nov; 212(5):682-691.

View in: PubMed
Newcomb LF, Schenk JM, Zheng Y, Liu M, Zhu K, Brooks JD, Carroll PR, Dash A, de la Calle CM, Ellis WJ, Filson CP, Gleave ME, Liss MA, Martin F, McKenney JK, Morgan TM, Tretiakova MS, Wagner AA, Nelson PS, Lin DW. Long-Term Outcomes in Patients Using Protocol-Directed Active Surveillance for Prostate Cancer. JAMA. 2024 06 25; 331(24):2084-2093.

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Saad F, Hussain MHA, Tombal B, Fizazi K, Sternberg CN, Crawford ED, Nordquist LT, B?gemann M, Tutrone R, Shore ND, Belkoff L, Fralich T, Jhaveri J, Srinivasan S, Li R, Verholen F, Kuss I, Smith MR. Deep and Durable Prostate-specific Antigen Response to Darolutamide with Androgen Deprivation Therapy and Docetaxel, and Association with Clinical Outcomes for Patients with High- or Low-volume Metastatic Hormone-sensitive Prostate Cancer: Analyses of the Randomized Phase 3 ARASENS Study. Eur Urol. 2024 Oct; 86(4):329-339.

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Bobbili PJ, Ivanova J, Solit DB, Mettu NB, McCall SJ, Dhawan M, DerSarkissian M, Arondekar B, Chang J, Niyazov A, Lee J, Huq R, Green M, Turski M, Lam P, Muthukumar A, Guo T, Mohan M, Zhang A, Duh MS, Oh WK. Treatment Patterns and Clinical Outcomes Among Patients With Metastatic Prostate Cancer Harboring Homologous Recombination Repair Mutations. Clin Genitourin Cancer. 2024 Jun; 22(3):102080.

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Vaishampayan UN, Keessen M, Dreicer R, Heath EI, Buchler T, ?rkosy PF, Cs?szi T, Wiechno P, Kopyltsov E, Orlov SV, Plekhanov A, Smagina M, Varlamov S, Shore ND. A global phase II randomized trial comparing oral taxane ModraDoc006/r to intravenous docetaxel in metastatic castration resistant prostate cancer. Eur J Cancer. 2024 May; 202:114007.

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Cooley LF, Srivastava A, Shore ND. Updates on Management of Biochemical Recurrent Prostate Cancer. Curr Treat Options Oncol. 2024 03; 25(3):284-292.

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Tutrone R, Saad F, George DJ, Tombal B, Bailen JL, Cookson MS, Saltzstein DR, Hanson S, Brown B, Lu S, Fallick M, Shore ND. Testosterone Recovery for Relugolix Versus Leuprolide in Men with Advanced Prostate Cancer: Results from the Phase 3 HERO Study. Eur Urol Oncol. 2024 Aug; 7(4):906-913.

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Efstathiou JA, Morgans AK, Bland CS, Shore ND. Novel hormone therapy and coordination of care in high-risk biochemically recurrent prostate cancer. Cancer Treat Rev. 2024 Jan; 122:102630.

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