Guanine Nucleotide Exchange Factors

"Guanine Nucleotide Exchange Factors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Protein factors that promote the exchange of GTP for GDP bound to GTP-BINDING PROTEINS.

Descriptor ID	D020662
MeSH Number(s)	D12.644.360.325.300 D12.776.476.325.300
Concept/Terms	Guanine Nucleotide Exchange Factors Guanine Nucleotide Exchange Factors Guanine-Nucleotide-Releasing Factor Guanine Nucleotide Releasing Factor GDP Dissociation Factor GDP-GTP Exchange Protein GDP GTP Exchange Protein GDP Dissociation Stimulators GDP-GTP Reversing Factors Factors, GDP-GTP Reversing GDP GTP Reversing Factors Reversing Factors, GDP-GTP Guanine Nucleotide Releasing Factors GDP Exchange Factors Exchange Factors, GDP Factors, GDP Exchange Guanine Nucleotide Exchange Factor

Below are MeSH descriptors whose meaning is more general than "Guanine Nucleotide Exchange Factors".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Intracellular Signaling Peptides and Proteins [D12.644.360]
GTP-Binding Protein Regulators [D12.644.360.325]
Guanine Nucleotide Exchange Factors [D12.644.360.325.300]
Proteins [D12.776]
Intracellular Signaling Peptides and Proteins [D12.776.476]
GTP-Binding Protein Regulators [D12.776.476.325]
Guanine Nucleotide Exchange Factors [D12.776.476.325.300]

Below are MeSH descriptors whose meaning is related to "Guanine Nucleotide Exchange Factors".

Below are MeSH descriptors whose meaning is more specific than "Guanine Nucleotide Exchange Factors".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Guanine Nucleotide Exchange Factors" by people in this website by year, and whether "Guanine Nucleotide Exchange Factors" was a major or minor topic of these publications.

Bar chart showing 28 publications over 17 distinct years, with a maximum of 3 publications in 2008 and 2009

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1997	0	1	1
1998	1	0	1
2003	0	1	1
2004	2	0	2
2005	0	1	1
2006	2	0	2
2007	1	1	2
2008	3	0	3
2009	2	1	3
2010	2	0	2
2011	1	1	2
2012	2	0	2
2013	0	1	1
2014	1	1	2
2016	0	1	1
2021	0	1	1
2022	0	1	1

Below are the most recent publications written about "Guanine Nucleotide Exchange Factors" by people in Profiles.

Choi S, Pandit SA, Nair AA, Greenstein V, Galetta SL, Brodie SE. Two cases of unilateral cone-rod dysfunction presenting in adult females. Doc Ophthalmol. 2022 12; 145(3):271-281.

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Merlo LMF, Peng W, DuHadaway JB, Montgomery JD, Prendergast GC, Muller AJ, Mandik-Nayak L. The Immunomodulatory Enzyme IDO2 Mediates Autoimmune Arthritis through a Nonenzymatic Mechanism. J Immunol. 2022 02 01; 208(3):571-581.

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Yang J, Wu C, Stefanescu I, Jakobsson L, Chervoneva I, Horowitz A. RhoA inhibits neural differentiation in murine stem cells through multiple mechanisms. Sci Signal. 2016 07 26; 9(438):ra76.

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Morgan SJ, Deshpande DA, Tiegs BC, Misior AM, Yan H, Hershfeld AV, Rich TC, Panettieri RA, An SS, Penn RB. ?-Agonist-mediated relaxation of airway smooth muscle is protein kinase A-dependent. J Biol Chem. 2014 Aug 15; 289(33):23065-23074.

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Barski JJ, Denker BM, Guan J, Lauth M, Spreafico F, Fertala A, Meyer M. Developmental upregulation of an alternative form of pcp2 with reduced GDI activity. Cerebellum. 2014 Apr; 13(2):207-14.

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Wilson AL, Schrecengost RS, Guerrero MS, Thomas KS, Bouton AH. Breast cancer antiestrogen resistance 3 (BCAR3) promotes cell motility by regulating actin cytoskeletal and adhesion remodeling in invasive breast cancer cells. PLoS One. 2013; 8(6):e65678.

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Ngok SP, Geyer R, Liu M, Kourtidis A, Agrawal S, Wu C, Seerapu HR, Lewis-Tuffin LJ, Moodie KL, Huveldt D, Marx R, Baraban JM, Storz P, Horowitz A, Anastasiadis PZ. VEGF and Angiopoietin-1 exert opposing effects on cell junctions by regulating the Rho GEF Syx. J Cell Biol. 2012 Dec 24; 199(7):1103-15.

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Janson C, Kasahara N, Prendergast GC, Colicelli J. RIN3 is a negative regulator of mast cell responses to SCF. PLoS One. 2012; 7(11):e49615.

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Singh M, Darcy KM, Brady WE, Clubwala R, Weber Z, Rittenbach JV, Akalin A, Whitney CW, Zaino R, Ramirez NC, Leslie KK. Cadherins, catenins and cell cycle regulators: impact on survival in a Gynecologic Oncology Group phase II endometrial cancer trial. Gynecol Oncol. 2011 Nov; 123(2):320-8.

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Wu C, Agrawal S, Vasanji A, Drazba J, Sarkaria S, Xie J, Welch CM, Liu M, Anand-Apte B, Horowitz A. Rab13-dependent trafficking of RhoA is required for directional migration and angiogenesis. J Biol Chem. 2011 Jul 01; 286(26):23511-20.

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