Platelet Membrane Glycoprotein IIb
"Platelet Membrane Glycoprotein IIb" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Platelet membrane glycoprotein IIb is an integrin alpha subunit that heterodimerizes with INTEGRIN BETA3 to form PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX. It is synthesized as a single polypeptide chain which is then postranslationally cleaved and processed into two disulfide-linked subunits of approximately 18 and 110 kDa in size.
| Descriptor ID |
D040201
|
| MeSH Number(s) |
D12.776.543.750.705.408.100.950
|
| Concept/Terms |
Platelet Membrane Glycoprotein IIb- Platelet Membrane Glycoprotein IIb
- Antigens, CD41
- CD41 Antigens
- CD41 Cell Surface Antigen
- GPalpha IIb
- GP IIb
- Membrane Glycoprotein IIb
- Glycoprotein IIb, Membrane
- Plasma Membrane Glycoprotein IIb
- Integrin alpha IIb
- Integrin alphaIIb
- alphaIIb, Integrin
- CD41 Antigen
- Antigen, CD41
- HUPL-ml Surface Antigen
- Antigen, HUPL-ml Surface
- HUPL ml Surface Antigen
- Surface Antigen, HUPL-ml
|
Below are MeSH descriptors whose meaning is more general than "Platelet Membrane Glycoprotein IIb".
Below are MeSH descriptors whose meaning is more specific than "Platelet Membrane Glycoprotein IIb".
This graph shows the total number of publications written about "Platelet Membrane Glycoprotein IIb" by people in this website by year, and whether "Platelet Membrane Glycoprotein IIb" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 1 | 0 | 1 |
| 2006 | 0 | 1 | 1 |
| 2007 | 0 | 2 | 2 |
| 2009 | 0 | 1 | 1 |
| 2012 | 0 | 2 | 2 |
| 2013 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Platelet Membrane Glycoprotein IIb" by people in Profiles.
-
Nakano H, Liu X, Arshi A, Nakashima Y, van Handel B, Sasidharan R, Harmon AW, Shin JH, Schwartz RJ, Conway SJ, Harvey RP, Pashmforoush M, Mikkola HK, Nakano A. Haemogenic endocardium contributes to transient definitive haematopoiesis. Nat Commun. 2013; 4:1564.
-
Welsh JD, Colace TV, Muthard RW, Stalker TJ, Brass LF, Diamond SL. Platelet-targeting sensor reveals thrombin gradients within blood clots forming in microfluidic assays and in mouse. J Thromb Haemost. 2012 Nov; 10(11):2344-53.
-
Thom SR, Milovanova TN, Bogush M, Bhopale VM, Yang M, Bushmann K, Pollock NW, Ljubkovic M, Denoble P, Dujic Z. Microparticle production, neutrophil activation, and intravascular bubbles following open-water SCUBA diving. J Appl Physiol (1985). 2012 Apr; 112(8):1268-78.
-
Navarro F, Gutman D, Meire E, Cáceres M, Rigoutsos I, Bentwich Z, Lieberman J. miR-34a contributes to megakaryocytic differentiation of K562 cells independently of p53. Blood. 2009 Sep 3; 114(10):2181-92.
-
Woulfe DS, Lilliendahl JK, August S, Rauova L, Kowalska MA, Abrink M, Pejler G, White JG, Schick BP. Serglycin proteoglycan deletion induces defects in platelet aggregation and thrombus formation in mice. Blood. 2008 Apr 01; 111(7):3458-67.
-
Aurigemma C, Fattorossi A, Sestito A, Sgueglia GA, Farnetti S, Buzzonetti A, Infusino F, Landolfi R, Scambia G, Crea F, Lanza GA. Relationship between changes in platelet reactivity and changes in platelet receptor expression induced by physical exercise. Thromb Res. 2007; 120(6):901-9.
-
Vijayan KV, Bray PF. Molecular mechanisms of prothrombotic risk due to genetic variations in platelet genes: Enhanced outside-in signaling through the Pro33 variant of integrin beta3. Exp Biol Med (Maywood). 2006 May; 231(5):505-13.
-
Vijayan KV, Liu Y, Li TT, Bray PF. Protein phosphatase 1 associates with the integrin alphaIIb subunit and regulates signaling. J Biol Chem. 2004 Aug 6; 279(32):33039-42.