GTP-Binding Protein alpha Subunits
"GTP-Binding Protein alpha Subunits" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The GTPase-containing subunits of heterotrimeric GTP-binding proteins. When dissociated from the heterotrimeric complex these subunits interact with a variety of second messenger systems. Hydrolysis of GTP by the inherent GTPase activity of the subunit causes it to revert to its inactive (heterotrimeric) form. The GTP-Binding protein alpha subunits are grouped into families according to the type of action they have on second messenger systems.
| Descriptor ID |
D044385
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| MeSH Number(s) |
D08.811.277.040.330.300.200.100 D12.644.360.360.100 D12.776.157.325.332.100 D12.776.476.375.100 D12.776.543.325.100
|
| Concept/Terms |
GTP-Binding Protein alpha Subunits- GTP-Binding Protein alpha Subunits
- GTP Binding Protein alpha Subunits
- G-Protein alpha Subunit
- G Protein alpha Subunit
- alpha Subunit, G-Protein
- GTP-Binding Protein alpha Subunit
- GTP Binding Protein alpha Subunit
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Below are MeSH descriptors whose meaning is more general than "GTP-Binding Protein alpha Subunits".
Below are MeSH descriptors whose meaning is more specific than "GTP-Binding Protein alpha Subunits".
This graph shows the total number of publications written about "GTP-Binding Protein alpha Subunits" by people in this website by year, and whether "GTP-Binding Protein alpha Subunits" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2007 | 1 | 1 | 2 |
| 2015 | 1 | 0 | 1 |
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Below are the most recent publications written about "GTP-Binding Protein alpha Subunits" by people in Profiles.
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Borgmann-Winter KE, Wang HY, Ray R, Willis BR, Moberg PJ, Rawson NE, Gur RE, Turetsky BI, Hahn CG. Altered G Protein Coupling in Olfactory Neuroepithelial Cells From Patients With Schizophrenia. Schizophr Bull. 2016 Mar; 42(2):377-85.
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McCusker E, Robinson AS. Refolding of G protein alpha subunits from inclusion bodies expressed in Escherichia coli. Protein Expr Purif. 2008 Apr; 58(2):342-55.
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Marrari Y, Crouthamel M, Irannejad R, Wedegaertner PB. Assembly and trafficking of heterotrimeric G proteins. Biochemistry. 2007 Jul 3; 46(26):7665-77.
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Evanko DS, Thiyagarajan MM, Takida S, Wedegaertner PB. Loss of association between activated Galpha q and Gbetagamma disrupts receptor-dependent and receptor-independent signaling. Cell Signal. 2005 Oct; 17(10):1218-28.
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Day PW, Wedegaertner PB, Benovic JL. Analysis of G-protein-coupled receptor kinase RGS homology domains. Methods Enzymol. 2004; 390:295-310.