"raf Kinases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of closely-related serine-threonine kinases that were originally identified as the cellular homologs of the retrovirus-derived V-RAF KINASES. They are MAP kinase kinase kinases that play important roles in SIGNAL TRANSDUCTION.
Descriptor ID |
D048490
|
MeSH Number(s) |
D08.811.913.696.620.682.700.559.842 D12.644.360.400.842 D12.776.476.400.842 D12.776.624.664.700.204
|
Concept/Terms |
raf Kinases- raf Kinases
- Kinases, raf
- raf Proto-Oncogene Proteins
- Proto-Oncogene Proteins, raf
- raf Proto Oncogene Proteins
- raf MAP Kinase Kinase Kinases
- raf Serine-Theonine Protein Kinases
- raf Serine Theonine Protein Kinases
- Proto-Oncogene Proteins raf
- Proteins raf, Proto-Oncogene
- Proto Oncogene Proteins raf
mil-raf Protein Kinases- mil-raf Protein Kinases
- Kinases, mil-raf Protein
- Protein Kinases, mil-raf
- mil raf Protein Kinases
- MIL-RAF Proteins
- MIL RAF Proteins
|
Below are MeSH descriptors whose meaning is more general than "raf Kinases".
Below are MeSH descriptors whose meaning is more specific than "raf Kinases".
This graph shows the total number of publications written about "raf Kinases" by people in this website by year, and whether "raf Kinases" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
---|
2006 | 0 | 2 | 2 |
2010 | 0 | 1 | 1 |
2011 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "raf Kinases" by people in Profiles.
-
Aplin AE, Kaplan FM, Shao Y. Mechanisms of resistance to RAF inhibitors in melanoma. J Invest Dermatol. 2011 Sep; 131(9):1817-20.
-
Shemon AN, Heil GL, Granovsky AE, Clark MM, McElheny D, Chimon A, Rosner MR, Koide S. Characterization of the Raf kinase inhibitory protein (RKIP) binding pocket: NMR-based screening identifies small-molecule ligands. PLoS One. 2010 May 05; 5(5):e10479.
-
Gilbert J, Argiris A. Emerging molecular targeted therapies in squamous cell carcinoma of the head and neck. Clin Adv Hematol Oncol. 2006 Aug; 4(8):611-9.
-
Codony-Servat J, Tapia MA, Bosch M, Oliva C, Domingo-Domenech J, Mellado B, Rolfe M, Ross JS, Gascon P, Rovira A, Albanell J. Differential cellular and molecular effects of bortezomib, a proteasome inhibitor, in human breast cancer cells. Mol Cancer Ther. 2006 Mar; 5(3):665-75.