MAP Kinase Kinase Kinase 5
"MAP Kinase Kinase Kinase 5" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 150-kDa MAP kinase kinase kinase that may play a role in the induction of APOPTOSIS. It has specificity for MAP KINASE KINASE 3; MAP KINASE KINASE 4; and MAP KINASE KINASE 6.
| Descriptor ID |
D048848
|
| MeSH Number(s) |
D08.811.913.696.620.682.700.559.500 D12.644.360.400.500 D12.776.476.400.500
|
| Concept/Terms |
MAP Kinase Kinase Kinase 5- MAP Kinase Kinase Kinase 5
- Apoptosis Signal-Regulating Kinase 1
- Apoptosis Signal Regulating Kinase 1
- MAPK Kinase Kinase 5
- MAP3K5 Protein Kinase
- Protein Kinase, MAP3K5
- Mitogen-Activated Kinase Kinase Kinase Kinase 5
- Mitogen Activated Kinase Kinase Kinase Kinase 5
- ASK1 Protein Kinase
- Protein Kinase, ASK1
- MAPKKK5
|
Below are MeSH descriptors whose meaning is more general than "MAP Kinase Kinase Kinase 5".
Below are MeSH descriptors whose meaning is more specific than "MAP Kinase Kinase Kinase 5".
This graph shows the total number of publications written about "MAP Kinase Kinase Kinase 5" by people in this website by year, and whether "MAP Kinase Kinase Kinase 5" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2009 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
| 2023 | 1 | 0 | 1 |
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Below are the most recent publications written about "MAP Kinase Kinase Kinase 5" by people in Profiles.
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Kostyak JC, McKenzie SE, Naik UP. The Function of ASK1 in Sepsis and Stress-Induced Disorders. Int J Mol Sci. 2023 Dec 22; 25(1).
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Zhang QS, Kurpad DS, Mahoney MG, Steinbeck MJ, Freeman TA. Inhibition of apoptosis signal-regulating kinase 1 alters the wound epidermis and enhances auricular cartilage regeneration. PLoS One. 2017; 12(10):e0185803.
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Yoon KW, Cho JH, Lee JK, Kang YH, Chae JS, Kim YM, Kim J, Kim EK, Kim SE, Baik JH, Naik UP, Cho SG, Choi EJ. CIB1 functions as a Ca(2+)-sensitive modulator of stress-induced signaling by targeting ASK1. Proc Natl Acad Sci U S A. 2009 Oct 13; 106(41):17389-94.
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Zhang H, Tao L, Jiao X, Gao E, Lopez BL, Christopher TA, Koch W, Ma XL. Nitrative thioredoxin inactivation as a cause of enhanced myocardial ischemia/reperfusion injury in the aging heart. Free Radic Biol Med. 2007 Jul 1; 43(1):39-47.
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Tao L, Jiao X, Gao E, Lau WB, Yuan Y, Lopez B, Christopher T, RamachandraRao SP, Williams W, Southan G, Sharma K, Koch W, Ma XL. Nitrative inactivation of thioredoxin-1 and its role in postischemic myocardial apoptosis. Circulation. 2006 Sep 26; 114(13):1395-402.
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He X, Liu Y, Sharma V, Dirksen RT, Waugh R, Sheu SS, Min W. ASK1 associates with troponin T and induces troponin T phosphorylation and contractile dysfunction in cardiomyocytes. Am J Pathol. 2003 Jul; 163(1):243-51.