Interferon Regulatory Factor-3
"Interferon Regulatory Factor-3" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An interferon regulatory factor that is expressed constitutively and undergoes POST-TRANSLATIONAL MODIFICATION following viral infection. PHOSPHORYLATION of IRF-3 causes the protein to be translocated from the CYTOPLASM to CELL NUCLEUS where it binds DNA, and activates transcription.
| Descriptor ID |
D050838
|
| MeSH Number(s) |
D12.644.360.024.302.374 D12.776.157.057.050.374 D12.776.260.504.374 D12.776.476.024.385.374 D12.776.744.562 D12.776.930.332.374
|
| Concept/Terms |
Interferon Regulatory Factor-3- Interferon Regulatory Factor-3
- Interferon Regulatory Factor 3
- IRF-3 Transcription Factor
- IRF 3 Transcription Factor
- Transcription Factor, IRF-3
- IFN-Regulatory Factor 3
- IFN Regulatory Factor 3
|
Below are MeSH descriptors whose meaning is more general than "Interferon Regulatory Factor-3".
Below are MeSH descriptors whose meaning is more specific than "Interferon Regulatory Factor-3".
This graph shows the total number of publications written about "Interferon Regulatory Factor-3" by people in this website by year, and whether "Interferon Regulatory Factor-3" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 0 | 1 | 1 |
| 2021 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Interferon Regulatory Factor-3" by people in Profiles.
-
Vazquez C, Swanson SE, Negatu SG, Dittmar M, Miller J, Ramage HR, Cherry S, Jurado KA. SARS-CoV-2 viral proteins NSP1 and NSP13 inhibit interferon activation through distinct mechanisms. PLoS One. 2021; 16(6):e0253089.
-
Fernandes-Alnemri T, Yu JW, Juliana C, Solorzano L, Kang S, Wu J, Datta P, McCormick M, Huang L, McDermott E, Eisenlohr L, Landel CP, Alnemri ES. The AIM2 inflammasome is critical for innate immunity to Francisella tularensis. Nat Immunol. 2010 May; 11(5):385-93.