"Cortactin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A microfilament protein that interacts with F-ACTIN and regulates cortical actin assembly and organization. It is also an SH3 DOMAIN containing phosphoprotein, and it mediates tyrosine PHOSPHORYLATION based SIGNAL TRANSDUCTION by PROTO-ONCOGENE PROTEIN PP60(C-SRC).
| Descriptor ID |
D051356
|
| MeSH Number(s) |
D05.750.078.730.281 D12.644.360.024.280 D12.776.157.057.014 D12.776.220.525.281 D12.776.476.024.311 D12.776.744.390
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Cortactin".
Below are MeSH descriptors whose meaning is more specific than "Cortactin".
This graph shows the total number of publications written about "Cortactin" by people in this website by year, and whether "Cortactin" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2011 | 2 | 0 | 2 |
To return to the timeline,
click here.
Below are the most recent publications written about "Cortactin" by people in Profiles.
-
Cheng L, Yung A, Covarrubias M, Radice GL. Cortactin is required for N-cadherin regulation of Kv1.5 channel function. J Biol Chem. 2011 Jun 10; 286(23):20478-89.
-
Snyder BN, Cho Y, Qian Y, Coad JE, Flynn DC, Cunnick JM. AFAP1L1 is a novel adaptor protein of the AFAP family that interacts with cortactin and localizes to invadosomes. Eur J Cell Biol. 2011 May; 90(5):376-89.