TCF Transcription Factors
"TCF Transcription Factors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of DNA-binding proteins that are primarily expressed in T-LYMPHOCYTES. They interact with BETA CATENIN and serve as transcriptional activators and repressors in a variety of developmental processes.
| Descriptor ID |
D051820
|
| MeSH Number(s) |
D12.776.260.730 D12.776.660.235.400.800 D12.776.664.235.400.800 D12.776.930.875
|
| Concept/Terms |
TCF Transcription Factors- TCF Transcription Factors
- Transcription Factors, TCF
- Lymphoid Enhancer Factors
- T-Cell Factors
- T Cell Factors
- LEF Transcription Factors
- Transcription Factors, LEF
|
Below are MeSH descriptors whose meaning is more general than "TCF Transcription Factors".
Below are MeSH descriptors whose meaning is more specific than "TCF Transcription Factors".
This graph shows the total number of publications written about "TCF Transcription Factors" by people in this website by year, and whether "TCF Transcription Factors" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2006 | 1 | 0 | 1 |
| 2009 | 1 | 0 | 1 |
| 2011 | 1 | 0 | 1 |
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Below are the most recent publications written about "TCF Transcription Factors" by people in Profiles.
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McCarthy TL, Kallen CB, Centrella M. ß-Catenin independent cross-control between the estradiol and Wnt pathways in osteoblasts. Gene. 2011 Jun 15; 479(1-2):16-28.
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Boman B, Kopelovich L, Siracusa LD, Zhang T, Henderson K, Cofer Z, Buchberg AM, Fields JZ, Otevrel T. A Tcf4-GFP reporter mouse model for monitoring effects of Apc mutations during intestinal tumorigenesis. Mol Carcinog. 2009 Sep; 48(9):821-31.
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Seki Y, Yamamoto H, Ngan CY, Yasui M, Tomita N, Kitani K, Takemasa I, Ikeda M, Sekimoto M, Matsuura N, Albanese C, Kaneda Y, Pestell RG, Monden M. Construction of a novel DNA decoy that inhibits the oncogenic beta-catenin/T-cell factor pathway. Mol Cancer Ther. 2006 Apr; 5(4):985-94.
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Sotgia F, Williams TM, Cohen AW, Minetti C, Pestell RG, Lisanti MP. Caveolin-1-deficient mice have an increased mammary stem cell population with upregulation of Wnt/beta-catenin signaling. Cell Cycle. 2005 Dec; 4(12):1808-16.
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Ghiselli G, Coffee N, Munnery CE, Koratkar R, Siracusa LD. The cohesin SMC3 is a target the for beta-catenin/TCF4 transactivation pathway. J Biol Chem. 2003 May 30; 278(22):20259-67.
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Sampson EM, Haque ZK, Ku MC, Tevosian SG, Albanese C, Pestell RG, Paulson KE, Yee AS. Negative regulation of the Wnt-beta-catenin pathway by the transcriptional repressor HBP1. EMBO J. 2001 Aug 15; 20(16):4500-11.