"Inflammasomes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Multiprotein complexes that mediate the activation of CASPASE-1. Dysregulation of inflammasomes has also been linked to a number of autoinflammatory and autoimmune disorders.
| Descriptor ID |
D058847
|
| MeSH Number(s) |
D05.500.224
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Inflammasomes".
Below are MeSH descriptors whose meaning is more specific than "Inflammasomes".
This graph shows the total number of publications written about "Inflammasomes" by people in this website by year, and whether "Inflammasomes" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 1 | 0 | 1 |
| 2011 | 1 | 0 | 1 |
| 2013 | 1 | 1 | 2 |
| 2019 | 1 | 0 | 1 |
| 2021 | 3 | 0 | 3 |
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Below are the most recent publications written about "Inflammasomes" by people in Profiles.
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Samukawa S, Yoshimi R, Kirino Y, Nakajima H. The PRY/SPRY domain of pyrin/TRIM20 interacts with ß2-microglobulin to promote inflammasome formation. Sci Rep. 2021 12 08; 11(1):23613.
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Ding R, Sun X, Yi B, Liu W, Kazama K, Xu X, Deshpande DA, Liang C, Sun J. Nur77 Attenuates Inflammasome Activation by Inhibiting Caspase-1 Expression in Pulmonary Vascular Endothelial Cells. Am J Respir Cell Mol Biol. 2021 09; 65(3):288-299.
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Mayes-Hopfinger L, Enache A, Xie J, Huang CL, Köchl R, Tybulewicz VLJ, Fernandes-Alnemri T, Alnemri ES. Chloride sensing by WNK1 regulates NLRP3 inflammasome activation and pyroptosis. Nat Commun. 2021 07 27; 12(1):4546.
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Rogers C, Erkes DA, Nardone A, Aplin AE, Fernandes-Alnemri T, Alnemri ES. Gasdermin pores permeabilize mitochondria to augment caspase-3 activation during apoptosis and inflammasome activation. Nat Commun. 2019 04 11; 10(1):1689.
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Park S, Juliana C, Hong S, Datta P, Hwang I, Fernandes-Alnemri T, Yu JW, Alnemri ES. The mitochondrial antiviral protein MAVS associates with NLRP3 and regulates its inflammasome activity. J Immunol. 2013 Oct 15; 191(8):4358-66.
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Fernandes-Alnemri T, Kang S, Anderson C, Sagara J, Fitzgerald KA, Alnemri ES. Cutting edge: TLR signaling licenses IRAK1 for rapid activation of the NLRP3 inflammasome. J Immunol. 2013 Oct 15; 191(8):3995-9.
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Fang R, Tsuchiya K, Kawamura I, Shen Y, Hara H, Sakai S, Yamamoto T, Fernandes-Alnemri T, Yang R, Hernandez-Cuellar E, Dewamitta SR, Xu Y, Qu H, Alnemri ES, Mitsuyama M. Critical roles of ASC inflammasomes in caspase-1 activation and host innate resistance to Streptococcus pneumoniae infection. J Immunol. 2011 Nov 1; 187(9):4890-9.
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Wu J, Fernandes-Alnemri T, Alnemri ES. Involvement of the AIM2, NLRC4, and NLRP3 inflammasomes in caspase-1 activation by Listeria monocytogenes. J Clin Immunol. 2010 Sep; 30(5):693-702.